alinastine
- CAS No.
- 154541-72-7
- Chemical Name:
- alinastine
- Synonyms
- alinastine;1H-Benzimidazole, 2-[1-[2-[4-(1,1-dimethylethyl)phenyl]ethyl]-4-piperidinyl]-1-(2-ethoxyethyl)-
- CBNumber:
- CB71332721
- Molecular Formula:
- C28H39N3O
- Molecular Weight:
- 433.636
- MDL Number:
- MOL File:
- 154541-72-7.mol
Boiling point | 574.2±50.0 °C(Predicted) |
---|---|
Density | 1.07±0.1 g/cm3(Predicted) |
pka | 8.78±0.10(Predicted) |
FDA UNII | FDP9A2F6YL |
alinastine Chemical Properties,Uses,Production
Originator
Alinastine ,Fabrica Espanola de Productos Quimicos y Farmaceuticos
Manufacturing Process
1.5 g of a sodium hydride suspension in oil are added to another suspension of 10.83 g of 2-[1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidin-4-yl]-1Hbenzimidazole in 150 ml of dimethylformamide and the mixture is stirred for 1 h at room temperature, then a solution of 2-(2-ethoxyethyl)tosylate in dimethylformamide are slowly added. The mixture is heated at 60°C for 16 h, poured onto water and extracted with ether. The extracts are washed with water, dried over anhydrous sodium sulfate and concentrated. The obtained oil is purified by column chromatography yielding 6.0 g of 1-(2-ethoxyethyl)-2- [1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidine-4-yl]-1H-benzimidazole, melting point 138°-140°C.
Therapeutic Function
Antihistaminic, Antiallergic
alinastine Preparation Products And Raw materials
Raw materials
Preparation Products
alinastine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19707 | 58 |
Supplier | Advantage |
---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | 58 |
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from alinastine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-28 | Alinastine
154541-72-7
|
US $2500.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. |
- Alinastine
154541-72-7
- US $2500.00-1980.00 / mg
- TargetMol Chemicals Inc.