D 595
- CAS No.
- 16740-29-7
- Chemical Name:
- D 595
- Synonyms
- D 595;Dichloroverapamil;2-(3,4-Dichlorophenyl)-2-isopropyl-5-[N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylamino]pentanenitrile;Benzeneacetonitrile, 3,4-dichloro-α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-α-(1-methylethyl)-
- CBNumber:
- CB71336224
- Molecular Formula:
- C25H32Cl2N2O2
- Molecular Weight:
- 463.44
- MDL Number:
- MOL File:
- 16740-29-7.mol
D 595 Chemical Properties,Uses,Production
Uses
D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET). Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers[1].
References
[1] Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters DOI:10.1021/acschemneuro.1c00078
D 595 Preparation Products And Raw materials
Raw materials
Preparation Products
D 595 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19710 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
