9-hydroxystearic acid
- CAS No.
- 3384-24-5
- Chemical Name:
- 9-hydroxystearic acid
- Synonyms
- 9-hydroxystearic acid;Octadecanoic acid, 9-hydroxy-
- CBNumber:
- CB71398266
- Molecular Formula:
- C18H36O3
- Molecular Weight:
- 300.48
- MDL Number:
- MFCD00192880
- MOL File:
- 3384-24-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H319-H317 | |||||||||
Precautionary statements | P261-P264-P272-P280-P302+P352-P305+P351+P338-P333+P313-P321-P337+P313-P363-P501 | |||||||||
NFPA 704 |
|
9-hydroxystearic acid Chemical Properties,Uses,Production
Definition
ChEBI: 9-hydroxyoctadecanoic acid is a hydroxyoctadecanoic acid that is octadecanoic acid (stearic acid) which has been substituted by a hydroxy group at position 9. It is a conjugate acid of a 9-hydroxyoctadecanoate.
Biological Activity
9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .1,2 It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.2 9-hydroxy Stearic acid (5 μM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.3 It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1 phase in, HT-29 cells when used at a concentration of 100 μM.1
References
1.Calonghi, N., Cappadone, C., Pagnotta, E., et al.9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cellsBiochem. Biophys. Res. Commun.314(1)138-142(2004) 2.Kolar, M.J., Kamat, S.S., Parsons, W.H., et al.Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipaseBiochemistry55(33)4636-4641(2016) 3.Calonghi, N., Cappadone, C., Pagnotta, E., et al.Histone deacetylase 1: A target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancerJ. Lipid Res.46(8)1596-1603(2005)
9-hydroxystearic acid Preparation Products And Raw materials
Raw materials
Preparation Products
9-hydroxystearic acid Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9639 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1859 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
Nanjing Chemlin Chemical Co., Ltd | 025-83697070 | info@chemlin.com.cn | China | 19172 | 64 |
Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9648 | 58 |
Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
View Lastest Price from 9-hydroxystearic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | 9-hydroxy Stearic Acid
3384-24-5
|
US $39.00-297.00 / mg | 99.7% | 10g | TargetMol Chemicals Inc. | |||
2024-07-20 | 9-hydroxystearic acid
3384-24-5
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
- 9-hydroxy Stearic Acid
3384-24-5
- US $39.00-297.00 / mg
- 99.7%
- TargetMol Chemicals Inc.
- 9-hydroxystearic acid
3384-24-5
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd