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9-hydroxystearic acid

CAS No.
3384-24-5
Chemical Name:
9-hydroxystearic acid
Synonyms
9-hydroxystearic acid;Octadecanoic acid, 9-hydroxy-
CBNumber:
CB71398266
Molecular Formula:
C18H36O3
Molecular Weight:
300.48
MDL Number:
MFCD00192880
MOL File:
3384-24-5.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

9-hydroxystearic acid Properties

Melting point 74-75 °C
Boiling point 433.9±28.0 °C(Predicted)
Density 0.944±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Chloroform: soluble
form A solid
pka 4.78±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H317
Precautionary statements  P261-P264-P272-P280-P302+P352-P305+P351+P338-P333+P313-P321-P337+P313-P363-P501
NFPA 704
0
2 0

9-hydroxystearic acid Chemical Properties,Uses,Production

Definition

ChEBI: 9-hydroxyoctadecanoic acid is a hydroxyoctadecanoic acid that is octadecanoic acid (stearic acid) which has been substituted by a hydroxy group at position 9. It is a conjugate acid of a 9-hydroxyoctadecanoate.

Biological Activity

9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .1,2 It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.2 9-hydroxy Stearic acid (5 μM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.3 It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1 phase in, HT-29 cells when used at a concentration of 100 μM.1

References

1.Calonghi, N., Cappadone, C., Pagnotta, E., et al.9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cellsBiochem. Biophys. Res. Commun.314(1)138-142(2004) 2.Kolar, M.J., Kamat, S.S., Parsons, W.H., et al.Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipaseBiochemistry55(33)4636-4641(2016) 3.Calonghi, N., Cappadone, C., Pagnotta, E., et al.Histone deacetylase 1: A target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancerJ. Lipid Res.46(8)1596-1603(2005)

112-80-1
3384-24-5
Synthesis of 9-hydroxystearic acid from Oleic acid

9-hydroxystearic acid Preparation Products And Raw materials

Raw materials

Preparation Products

9-hydroxystearic acid Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3958 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9639 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
VladaChem GmbH
+49-7246-3082843 info@vladachem.de Germany 1859 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
Nanjing Chemlin Chemical Co., Ltd 025-83697070 info@chemlin.com.cn China 19172 64
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9648 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60

View Lastest Price from 9-hydroxystearic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
9-hydroxy Stearic Acid pictures 2024-11-19 9-hydroxy Stearic Acid
3384-24-5
US $39.00-297.00 / mg 99.7% 10g TargetMol Chemicals Inc.
9-hydroxystearic acid pictures 2024-07-20 9-hydroxystearic acid
3384-24-5
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
9-hydroxystearic acid Octadecanoic acid, 9-hydroxy- 3384-24-5