Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol Structure
4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol structure
CAS No.
68592-15-4
Chemical Name:
4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol
Synonyms
4-O-Methyl honokiol;4'-O-Methylhonokiol;4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol;4'-Methoxy-3',5-di-2-propen-1-yl[1,1'-biphenyl]-2-ol;2-(4-methoxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol;[1,1'-Biphenyl]-2-ol, 4'-methoxy-3',5-di-2-propen-1-yl-
CBNumber:
CB71401542
Molecular Formula:
C19H20O2
Molecular Weight:
280.36
MDL Number:
MFCD19705288
MOL File:
68592-15-4.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:36
Request For Quotation

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol Properties

storage temp. Store at -20°C
solubility DMF: 33 mg/ml; DMSO: 33 mg/ml; Ethanol: 33 mg/ml; Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
form Viscous Liquid
color Orange to red
FDA UNII TUH6B83HJW

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
3
0 0

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0035406 4-O-Methylhonokiol 99.65% 68592-15-4 5mg $450 2021-12-16 Buy
ChemScene CS-0035406 4-O-Methylhonokiol 99.65% 68592-15-4 10mg $800 2021-12-16 Buy
Product number Packaging Price Buy
CS-0035406 5mg $450 Buy
CS-0035406 10mg $800 Buy

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol Chemical Properties,Uses,Production

Uses

4-O-Methyl honokiol is a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist, and inhibtis NF-κB activity, used for cancer and inflammation research.

in vivo

4-O-Methyl honokiol (40 or 80 mg/kg, i.p. everyday for 4 weeks) inhibits the growth of SW620 and PC3 tumours in SW620 and PC3 xenograft model. 4-O-Methyl honokiol significantly increases the expression of p21 and PPARγ in the tumour tissues[1]. 4-O-Methyl honokiol (0.5 or 1 mg/kg/day daily for 3 weeks) significantly ameliorates LPS-induced memory impairment, and inhibits LPS-induced iNOS and COX-2 expression in mice. 4-O-Methyl honokiol also shows inhibitory activities against the Aβ1-42 accumulation, and activates astrocytes and microglia in LPS-injected mice brain[2].

IC 50

PPARγ; NF-κB

References

[1] Lee NJ, et al. 4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity. Br J Pharmacol. 2013 Mar;168(5):1133-45. DOI:10.1111/j.1476-5381.2012.02235.x
[2] Lee YJ, et al. Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. J Neuroinflammation. 2012 Feb 19;9:35. DOI:10.1186/1742-2094-9-35

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol Suppliers

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3989 66
Wuhan HengHeDa Pharm Co., Ltd. 27-27-84888682 18086046872 hhdpharm@hotmail.com China 104 55
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 shenlinxing@macklin.cn China 15874 55
Supplier Advantage
Wuhan ChemNorm Biotech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		58
Shanghai Tauto Biotech Co., Ltd. 66
Wuhan HengHeDa Pharm Co., Ltd. 55
Shanghai Macklin Biochemical Co.,Ltd. 55

View Lastest Price from 4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-O-Methyl honokiol pictures 2024-11-19 4-O-Methyl honokiol
68592-15-4
 US $52.00-197.00 / mg 99.31% 10g TargetMol Chemicals Inc.
4-O-Methyl honokiol pictures 2024-11-19 4-O-Methyl honokiol
68592-15-4
 US $52.00-197.00 / mg 99.31% 10g TargetMol Chemicals Inc.
4'-Methoxy-3',5-di-2-propenyl-(1,1'-biphenyl)-2-ol 2-(4-methoxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol 4-O-Methyl honokiol [1,1'-Biphenyl]-2-ol, 4'-methoxy-3',5-di-2-propen-1-yl- 4'-Methoxy-3',5-di-2-propen-1-yl[1,1'-biphenyl]-2-ol 4'-O-Methylhonokiol 68592-15-4 8592-15-4 novel chemicals