Triclocarban
- CAS No.
- 101-20-2
- Chemical Name:
- Triclocarban
- Synonyms
- TCC;TRICHLOROCARBANILIDE;TRICHLOCARBAN;3,4,4 TRICHLOROCARBANILIDE;cusiter;CUTISAN;CP 78416;ent26925;genoface;Nobacter
- CBNumber:
- CB7193925
- Molecular Formula:
- C13H9Cl3N2O
- Molecular Weight:
- 315.58
- MDL Number:
- MFCD00013254
- MOL File:
- 101-20-2.mol
- MSDS File:
- SDS
| Melting point | 254-256 °C (lit.) |
|---|---|
| Boiling point | 344.2±42.0 °C(Predicted) |
| Density | 1.5732 (rough estimate) |
| vapor pressure | <0.1 mm Hg ( 25 °C) |
| refractive index | 1.6300 (estimate) |
| Flash point | 150 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble |
| pka | 12.77±0.70(Predicted) |
| form | Solid |
| color | Fine plates |
| Water Solubility | <0.1 g/100 mL at 26 ºC |
| Merck | 14,9654 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents strong bases. |
| InChIKey | ICUTUKXCWQYESQ-UHFFFAOYSA-N |
| LogP | 3.633 at 25℃ |
| CAS DataBase Reference | 101-20-2(CAS DataBase Reference) |
| FDA 21 CFR | 310.545 |
| EWG's Food Scores | 2-3 |
| FDA UNII | BGG1Y1ED0Y |
| NIST Chemistry Reference | 3,4,4'-Trichloro carbanilide(101-20-2) |
| EPA Substance Registry System | Triclocarban (101-20-2) |
| Cosmetics Info | Triclocarban |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H410 | |||||||||
| Precautionary statements | P273-P501 | |||||||||
| Hazard Codes | N | |||||||||
| Risk Statements | 50/53 | |||||||||
| Safety Statements | 60-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | FE1250000 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 38220090 | |||||||||
| Hazardous Substances Data | 101-20-2(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 ipr-mus: 2100 mg/kg LPPTAK 27,306,79 | |||||||||
| NFPA 704 |
|
Triclocarban price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 105937 | 3,4,4′-Trichlorocarbanilide 99% | 101-20-2 | 5g | $23.48 | 2024-03-01 | Buy |
| Sigma-Aldrich | 105937 | 3,4,4′-Trichlorocarbanilide 99% | 101-20-2 | 100g | $98 | 2024-03-01 | Buy |
| Sigma-Aldrich | 05666 | Triclocarban analytical standard | 101-20-2 | 25MG | $84.5 | 2024-03-01 | Buy |
| TCI Chemical | T1015 | 3,4,4'-Trichlorocarbanilide >98.0%(HPLC)(N) | 101-20-2 | 25g | $48 | 2024-03-01 | Buy |
| TCI Chemical | T1015 | 3,4,4'-Trichlorocarbanilide >98.0%(HPLC)(N) | 101-20-2 | 500g | $317 | 2024-03-01 | Buy |
Triclocarban Chemical Properties,Uses,Production
Chemical Properties
white crystals or powder
Originator
Cutisan,Innothera,France,1960
Uses
Used as bacteriostat and antiseptic in soaps and other cleansing compositions. Antiseptic, disinfectant.
Uses
Labelled Triclocarban
Definition
ChEBI: A member of the class of ureas that is urea substituted by a 4-chlorophenyl and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
Manufacturing Process
To a suitable reaction vessel equipped with a thermometer, agitator and reflux condenser and containing 8.1 parts by weight (substantially 0.05 mol) of 3,4-dichloroaniline in approximately 57 parts by weight of diethyl ether is added dropwise a solution of 7.7 parts by weight (substantially 0.05 mol) of 4- chlorophenyl isocyanate in approximately 15 parts by weight of diethyl ether at such a rate so as to maintain gentle reflux. Upon completion of the isocyanate addition the reaction mass is agitated for about one hour. The mass is filtered and the residue washed with diethyl ether. The dried product is a white fluffy solid which on recrystallization from ethanol gives fine white plates of 4,3',4'-trichlorocarbanilide, melting point 255.2°C to 256.0°C (88.0% yield)
Therapeutic Function
Disinfectant
General Description
Fine white plates or white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A halogenated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard
The flash point of Triclocarban has not been determined. Triclocarban is, however, probably combustible.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
3,4,4′-Trichlorocarbanilide interferes with mammalian reproduction and can cause methemoglobinemia in humans.
Safety Profile
Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of Clí and NOx.
Triclocarban Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5887 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18147 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3007 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1015 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| Hebei Junhua Import and Export Co., LTD | +86-18503288844 +86-18503288844 | junhua1@hb-junhua.com | China | 420 | 58 |
View Lastest Price from Triclocarban manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-22 | Triclocarban
101-20-2
|
US $0.00 / kg | 1kg | 99% | 1000 | Hebei Junhua Import and Export Co., LTD | |
 |
2025-02-21 | Triclosan
101-20-2
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2025-02-21 | Triclocarban TCC
101-20-2
|
US $85.00-35.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- Triclocarban
101-20-2
- US $0.00 / kg
- 99%
- Hebei Junhua Import and Export Co., LTD
-
- Triclosan
101-20-2
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- Triclocarban TCC
101-20-2
- US $85.00-35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd