Homovanillic acid
- CAS No.
- 306-08-1
- Chemical Name:
- Homovanillic acid
- Synonyms
- HVA;Homovanilic acid;4-HYDROXY-3-METHOXYPHENYLACETIC ACID;4-Hydroxy-3-methoxybenzeneacetic acid;Benzeneacetic acid, 4-hydroxy-3-methoxy-;JACS-306-08-1;homovanillicaci;Vanilacetic acid;HOMOVANIUIC ACID;HOMORANILLIC ACID
- CBNumber:
- CB7198081
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00004350
- MOL File:
- 306-08-1.mol
- MSDS File:
- SDS
| Melting point | 142-145 °C(lit.) |
|---|---|
| Boiling point | 235.56°C (rough estimate) |
| Density | 1.1634 (rough estimate) |
| refractive index | 1.4209 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Crystalline Powder |
| pka | 4.39±0.10(Predicted) |
| color | White to beige |
| Water Solubility | soluble |
| Merck | 14,4740 |
| BRN | 2213447 |
| Stability | Hygroscopic |
| LogP | 0.330 |
| CAS DataBase Reference | 306-08-1(CAS DataBase Reference) |
| FDA UNII | X77S6GMS36 |
| NIST Chemistry Reference | Benzeneacetic acid, 4-hydroxy-3-methoxy-(306-08-1) |
| EPA Substance Registry System | Homovanillic acid (306-08-1) |
| UNSPSC Code | 77101502 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
Homovanillic acid price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H1252 | Homovanillic acid Fluorimetric reagent | 306-08-1 | 1g | $92.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69673 | Homovanillic acid analytical standard | 306-08-1 | 25mg | $71.4 | 2024-03-01 | Buy |
| TCI Chemical | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) | 306-08-1 | 1g | $42 | 2024-03-01 | Buy |
| TCI Chemical | H0339 | 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) | 306-08-1 | 5g | $141 | 2024-03-01 | Buy |
| Alfa Aesar | A12441 | Homovanillic acid, 98+% | 306-08-1 | 1g | $72.4 | 2024-03-01 | Buy |
Homovanillic acid Chemical Properties,Uses,Production
Description
Homovanillic acid (HVA) is a dopamine metabolite. It is formed via deamination of dopamine by monoamine oxidase (MAO) to produce 3,4-dihydroxyphenylacetic acid (DOPAC; ) followed by DOPAC metabolism by catechol-O-methyltransferase (COMT). HVA undergoes hydrogen peroxide-dependent oxidation in the presence of horseradish peroxidase to form a fluorescent dimer that displays excitation/emission maxima of 312/420 nm, respectively. It has been used to quantify hydrogen peroxide production in macrophages and neutrophils.
Chemical Properties
white to beige crystalline powder
Uses
A neuroendocrine tumor marker. Dihydroxyphenylacetic Acid (DOPAC) metabolite.
Uses
Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.
Definition
ChEBI: A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Biological Activity
Fluorimetric reagent and major catecholamine metabolite. Used for fluorimetric determination of oxidative enzymes including glucose oxidase.
storage
+4°C
Homovanillic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from Homovanillic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-21 | Chromic sulfate
306-08-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2024-11-19 | Homovanillic acid
306-08-1
|
US $57.00 / mg | 98.93% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Homovanillic acid
306-08-1
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Chromic sulfate
306-08-1
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Homovanillic acid
306-08-1
- US $57.00 / mg
- 98.93%
- TargetMol Chemicals Inc.
-
- Homovanillic acid
306-08-1
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.