Anti-Humanin (HN) antibody produced in rabbit

Uses

Anti-Humanin (HN) antibody produced in rabbit has been used in:

• immunohistochemistry
• immunoprecipitation (1:300)
• fluorescent immunohistochemistry (1:300)
• immunoblotting (1:500)

General Description

Humanin (HN) is a small polypeptide, derived from mitochondria. This protein is secreted by various cells and is localized in the plasma and bound to the cell membranes.

Biochem/physiol Actions

Humanin (HN) acts as a neuroprotective factor. It is involved in promoting cell survival. Humanin suppresses cell death in the neuronal cells caused by Alzheimer′s disease-related insults like anti-amyloid- precursor protein antibody, neurotoxic amyloid β (Aβ) peptides, and familial Alzheimer disease proteins.