AMBRETTOLIDE
- CAS No.
- 28645-51-4
- Chemical Name:
- AMBRETTOLIDE
- Synonyms
- Nsc 31697;FEMA 2555;AMBRETTOLIDE;Fema no. 2555;Einecs 249-120-7;HEXADECEN-8-OLIDE;Ambrettolide 1832003;OMEGA-6-HEXADECENLACTONE;Oxacycloheptadec-10-en-2-on;1-oxacycloheptadec-10-en-2-one
- CBNumber:
- CB7213218
- Molecular Formula:
- C16H28O2
- Molecular Weight:
- 252.39
- MDL Number:
- MFCD00022326
- MOL File:
- 28645-51-4.mol
| Boiling point | 185-190 °C16 mm Hg(lit.) |
|---|---|
| Density | 0.956 g/mL at 25 °C(lit.) |
| vapor pressure | 0.003Pa at 25℃ |
| refractive index |
n |
| FEMA | 4145 | ISOAMBRETTOLIDE |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | Oil |
| color | Clear Colorless |
| Odor | at 10.00 % in dipropylene glycol. sweet musk ambrette fruity waxy fatty |
| Odor Type | musk |
| Water Solubility | 15μg/L at 25℃ |
| JECFA Number | 1991 |
| LogP | 6.7 at 23℃ |
| Substances Added to Food (formerly EAFUS) | ISOAMBRETTOLIDE |
| EWG's Food Scores | 2 |
| FDA UNII | 0DI2GU512F |
| EPA Substance Registry System | Oxacycloheptadec-10-en-2-one (28645-51-4) |
| UNSPSC Code | 12164502 |
| NACRES | NA.21 |
AMBRETTOLIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W414522 | Isoambrettolide ≥97%, FG | 28645-51-4 | SAMPLE-K | $50 | 2024-03-01 | Buy |
| Sigma-Aldrich | W414522 | Isoambrettolide ≥97%, FG | 28645-51-4 | 100g | $70 | 2024-03-01 | Buy |
| Sigma-Aldrich | W414522 | Isoambrettolide ≥97%, FG | 28645-51-4 | 1kg | $400 | 2024-03-01 | Buy |
| Sigma-Aldrich | W414522 | Isoambrettolide ≥97%, FG | 28645-51-4 | 100G-K | $70 | 2023-06-20 | Buy |
| Sigma-Aldrich | W414522 | Isoambrettolide ≥97%, FG | 28645-51-4 | 1KG-K | $400 | 2023-06-20 | Buy |
AMBRETTOLIDE Chemical Properties,Uses,Production
Aroma
Colorless, somewhat viscous oil with rich and
extremely tenacious floral-musky, sweet odor.
Ambrettolide is one of the finest fixatives among the distinguished group of those showing a synergistic and amplifying effect upon perfumes and flavors. At the same time it increases the diffusiveness of fragrances in which it is incorporated. Its fixative effect is easily recognized by the fact that solutions of 0.01% ~ Ambrettolide (or even less) in slightly diluted alcohol show practically no odor of alcohol, only a faint, floral-musky, sweet and pleasant odor of the lactone. A. is particularly useful in fragrance types of delicately floral, mildly animal or Ambre-like type.
Chemical Properties
AMBRETTOLIDE is not reported as being found in nature, in contrast to (Z)-7-hexadecen-16-olide, which occurs in ambrette seed oil and which is also referred to as ambrettolide. It is a colorless to slightly yellow liquid, d204 0.949–0.957, n20D 1.477–1.482, with an intense and powerful musk odor. It is prepared by treating aleuritic acid (9,10,16-trihydroxyhexadecanoic acid) with trimethyl orthoformate to give a dioxolane derivative. Reaction with acetic anhydride yields ??-acetoxy (E)-9-hexadecenoic acid methyl ester. This is lactonized with potassium hydroxide to give the title compound .
Occurrence
Found in oil of ambrette seed[Givaudan Index, 1961).
Uses
Ambrettolide is a macrocyclic lactone that naturally occurs in ambrette seed oil. Ambrettolide is nontoxic, has a musky odour, and is commonly used as a fixative in perfume formulations.
Production Methods
Many patented methods are known, few are commercially feasible. From Bromo hexadecenoic acid, or from Dihydroxy palmitic acid, or from Aleuritic acid, or from Juniperic acid, etc.
Preparation
From bromohexadecenoic acid(Bedoukian, 1967).
Definition
ChEBI: Isoambrettolide is a macrolide.
Flammability and Explosibility
Not classified
AMBRETTOLIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2251 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20234 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from AMBRETTOLIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-13 | AMBRETTOLIDE
28645-51-4
|
US $15.00-10.00 / kg | 1kg | 99.99% | 10 tons | Shandong Deshang Chemical Co., Ltd. | |
 |
2019-12-20 | AMBRETTOLIDE
28645-51-4
|
US $2.00 / KG | 1KG | 98%min | ask | Career Henan Chemical Co |
-
- AMBRETTOLIDE
28645-51-4
- US $15.00-10.00 / kg
- 99.99%
- Shandong Deshang Chemical Co., Ltd.
-
- AMBRETTOLIDE
28645-51-4
- US $2.00 / KG
- 98%min
- Career Henan Chemical Co