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CDK2 INHIBITOR II

CDK2 INHIBITOR II structure

CAS No.: 222035-13-4

Chemical Name:: CDK2 INHIBITOR II

Synonyms: SC 221409;COMPOUND 3;CDK2 INHIBITOR II;CDK2-IN-3 (compound 3);SC 221409, Cdk2 inhibitor;4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide;4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide;Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-

CBNumber:: CB7244623

Molecular Formula:: C14H11BrN4O3S

Molecular Weight:: 395.23

MDL Number:: MFCD24369028

MOL File:: 222035-13-4.mol

Last updated:2025-01-27 09:38:02

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CDK2 INHIBITOR II Properties

Melting point	>272°C (dec.)
Density	1.85±0.1 g/cm3(Predicted)
storage temp.	Amber Vial, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	8.81±0.20(Predicted)
color	Light Orange to Orange
UNSPSC Code	12352200

CDK2 INHIBITOR II price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	15154	Cdk2 Inhibitor II ≥95%	222035-13-4	500μg	$32	2024-03-01	Buy
Cayman Chemical	15154	Cdk2 Inhibitor II ≥95%	222035-13-4	1mg	$57	2024-03-01	Buy
Cayman Chemical	15154	Cdk2 Inhibitor II ≥95%	222035-13-4	5mg	$166	2024-03-01	Buy
TRC	C228120	CDK2inhibitorII	222035-13-4	10mg	$120	2021-12-16	Buy
AK Scientific	6150CK	Cdk2InhibitorII	222035-13-4	5mg	$282	2021-12-16	Buy

Product number	Packaging	Price	Buy
15154	500μg	$32	Buy
15154	1mg	$57	Buy
15154	5mg	$166	Buy
C228120	10mg	$120	Buy
6150CK	5mg	$282	Buy

CDK2 INHIBITOR II Chemical Properties,Uses,Production

Description

The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G₂-M transition during the cell cycle. Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC₅₀ = 60 nM). It is cell permeable, reversible, and ATP-competitive.

Uses

CDK2 inhibitor II, is a potent, cell-permeable, ATP-competitive, and selective inhibitor of Cdk2.

CDK2 INHIBITOR II Preparation Products And Raw materials

Raw materials

Preparation Products

CDK2 INHIBITOR II Suppliers

Global( 34)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Suzhou Su Taike Biological Reagent Co., Ltd.	18352410772	seetech@126.com	China	6	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94657	76
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9477	58
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8065	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4999	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57423	58

Supplier	Advantage
Aladdin Scientific	58
Suzhou Su Taike Biological Reagent Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
VDM Biochemicals	64
Shanghai Topbiochem Technology Co., Ltd	58
Shanghai TaoSu Biochemical Technology Co., Ltd.	58
BOC Sciences	65
MQ (shanghai) Pharmaceuticals Co., Ltd.	55
Shanghai Hongye Biotechnology Co. Ltd	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58

COMPOUND 3 CDK2 INHIBITOR II SC 221409 Benzenesulfonamide, 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]- CDK2-IN-3 (compound 3) 4-(2-(5-Bromo-2-oxoindolin-3-ylidene)hydrazinyl)benzenesulfonamide 4-[2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-benzenesulfonamide SC 221409, Cdk2 inhibitor 222035-13-4 Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals