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ChemicalBook >> CAS DataBase List >>5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Structure
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone structure
CAS No.
173140-90-4
Chemical Name:
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
Synonyms
(R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one;BNKY004-IM01;8-benzoxy-5-(R)-oxiranyl-1H-quinolin-2-one;5-(2R) -2-epoxyl-8-benzoxy-2 (1H) -quinolone;5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone;(R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone;2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone;8-(Benzyloxy)-5-[(2R)-oxiran-2-yl]quinolin-2(1H)-one;2(1H)-Quinolinone, 5-(2R)-oxiranyl-8-(phenylmethoxy)-;5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone
CBNumber:
CB72516579
Molecular Formula:
C18H15NO3
Molecular Weight:
293.32
MDL Number:
MFCD17018704
MOL File:
173140-90-4.mol
Last updated:2023-11-06 16:47:05
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5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Properties

Melting point 155 - 157°C
Boiling point 556.0±50.0 °C(Predicted)
Density 1.298
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.92±0.70(Predicted)
form Solid
color White to Pale Yellow
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B194026 (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one 173140-90-4 10mg $45 2021-12-16 Buy
TRC B194026 (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one 173140-90-4 100mg $195 2021-12-16 Buy
American Custom Chemicals Corporation CCH0032983 (R)-8-(BENZYLOXY)-5-(OXIRAN-2-YL)QUINOLIN-2(1H)-ONE 95.00% 173140-90-4 25MG $226.8 2021-12-16 Buy
Oakwood 212988 (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one 95+% 173140-90-4 1g $420 2021-12-16 Buy
AK Scientific J11352 IndacaterolImpurity5 173140-90-4 25mg $45 2021-12-16 Buy
Product number Packaging Price Buy
B194026 10mg $45 Buy
B194026 100mg $195 Buy
CCH0032983 25MG $226.8 Buy
212988 1g $420 Buy
J11352 25mg $45 Buy

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Chemical Properties,Uses,Production

Uses

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_173140-90-4
A 5 liter flask equipped with a mechanical stirrer, thermometer, and refluxing condenser was charged with 8-benzyloxy-5-[(R)-(2-bromo-1-hydroxyethyl)]-carbostyriI (70gms/0.187 moles), potassium carbonate (74 gmsl 0.536 moles), acetone (3.5 liters) and water (35 ml). The resulting slurry 'was heated to reflux and maintained for 2% hours. After completion of reaction, the hot mass was filtered on hylo bed to remove inorganics. The residue was slurried in dichloromethane (200 ml) and filtered on hyflo bed. The filtrates were combined together and concentrated under vacuum completely. The residue was dissolved. in dichloromethane (500ml) and filtered on hyflo bed to remove traces of insolubles and washed with dichloromethane(100 ml). The clear filtrate was distilled completely to obtain residue. The residue was charged with methanol (70 ml), stirred and heated to 50??C for 30 minutes. The slurry obtained was cooled to 25-30??C,chilled to 0- 5??C, stirred for 1 hour. The resulting solid was isolated by filtration, washed with methanol (30ml), followed by diisopropylether (100ml) and dried under vacuum at 60-65 ??C for 10-12 hours to yield 40-41 gms of 8-benzyloxy- 5-(R)-oxiranylcarbostyril.

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone synthesis

100331-89-3
173140-90-4
Synthesis of 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone from 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline

Preparation Products

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Suppliers

Global( 176)Suppliers
Supplier Tel Email Country ProdList Advantage
BIONNA MEDICINE CO.,LTD
01056380788-8515; +8618518759099 790226113@qq.com China 52 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18774 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2136 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2963 58
Supplier Advantage
BIONNA MEDICINE CO.,LTD
58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Nanjing Finetech Chemical Co., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Jinan Finer Chemical Co., Ltd 		58

View Lastest Price from 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone pictures 2024-08-27 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
173140-90-4
 US $65.00-650.00 / kg 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone pictures 2022-10-01 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
173140-90-4
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone pictures 2019-09-05 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
173140-90-4
 US $1.00 / KG 1KG 98% 1000KG Career Henan Chemical Co

173140-90-4(5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone)Related Search:

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2(1H)-Quinolinone, 5-(2R)-oxiranyl-8-(phenylmethoxy)- 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Indacaterol interMediate :2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 8-(Benzyloxy)-5-[(2R)-oxiran-2-yl]quinolin-2(1H)-one 2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 8-benzoxy-5-(R)-oxiranyl-1H-quinolin-2-one (R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone BNKY004-IM01 5-[(2R)-oxiran-2-yl]-8-phenylmethoxy-1H-quinolin-2-one 2(1H)-Quinolinone, 5-(2R)-2-oxiranyl-8-(phenylmethoxy)- 8-(benzyloxy)-5-((1R)-2-((5-ethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one fumarate (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one( Indacaterol Impurity 5) (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one 5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone 5- (2R) -2-epoxyethanyl-8-benzyloxy-2 (1H) - quinolone 5-(2R) -2-epoxyl-8-benzoxy-2 (1H) -quinolone 173140-90-4