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SC-1

SC-1 structure

CAS No.: 1313019-65-6

Chemical Name:: SC-1

Synonyms: SC-1;Compound SC-1;SC-1 >=98% (HPLC);1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea;Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[4-(4-cyanophenoxy)phenyl]-;1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, 10 mM in DMSO;STAT,cyclin-D1,Inhibitor,inhibit,kinase,Apoptosis,1(4Chloro3(trifluoromethyl)phenyl)3(4(4cyanophenoxy)phenyl)urea,p-STAT3,orally,anticancer,SHP-1,1 (4 Chloro 3 (trifluoromethyl)phenyl) 3 (4 (4 cyanophenoxy)phenyl)urea,survivin

CBNumber:: CB72520383

Molecular Formula:: C21H13ClF3N3O2

Molecular Weight:: 431.8

MDL Number:: MFCD27665015

MOL File:: 1313019-65-6.mol

Last updated:2025-01-27 09:38:02

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SC-1 Properties

storage temp.	2-8°C
solubility	DMSO: soluble15mg/mL, clear
form	powder
color	white to beige
Water Solubility	Water: Insoluble
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H413
Precautionary statements	P273-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
WGK Germany	3

SC-1 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0858	SC-1 ≥98% (HPLC)	1313019-65-6	5mg	$104	2024-03-01	Buy
Sigma-Aldrich	SML0858	SC-1 ≥98% (HPLC)	1313019-65-6	25mg	$409	2023-01-07	Buy

Product number	Packaging	Price	Buy
SML0858	5mg	$104	Buy
SML0858	25mg	$409	Buy

SC-1 Chemical Properties,Uses,Production

Biological Activity

SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib with no kinase-inhibition activity. SC-1 blocks STAT3 phosphorylation and activation with similar potency to sorafenib, and induces apoptosis in hepatocellular carcinoma cell lines.

SC-1 synthesis

Synthesis of SC-1 from Triphosgene and 4-(4-aminophenoxy)benzonitrile and 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine

SC-1 Preparation Products And Raw materials

Raw materials

4-(4-aminophenoxy)benzonitrile 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine Triphosgene

Preparation Products

SC-1 Suppliers

Global( 65)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30231	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2922	55
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71829	60
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	9310	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Aladdin Scientific	58
Shanghai Boyle Chemical Co., Ltd.	55
BOC Sciences	65
Shanghai YuanYe Biotechnology Co., Ltd.	60
ShangHai Biochempartner Co.,Ltd	62
Shanghai Chaolan Chemical Technology Center	58

View Lastest Price from SC-1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Compound SC-1 1313019-65-6	US $139.00-428.00 / mg		99.41%	10g	TargetMol Chemicals Inc.

Compound SC-1
1313019-65-6
US $139.00-428.00 / mg
99.41%
TargetMol Chemicals Inc.

1313019-65-6(SC-1)Related Search:

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4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

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SC-1 N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[4-(4-cyanophenoxy)phenyl]- SC-1 >=98% (HPLC) 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea STAT,cyclin-D1,Inhibitor,inhibit,kinase,Apoptosis,1(4Chloro3(trifluoromethyl)phenyl)3(4(4cyanophenoxy)phenyl)urea,p-STAT3,orally,anticancer,SHP-1,1 (4 Chloro 3 (trifluoromethyl)phenyl) 3 (4 (4 cyanophenoxy)phenyl)urea,survivin Compound SC-1 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, 10 mM in DMSO 1313019-65-6 C21H13ClF3N3O2