ChemicalBook >> CAS DataBase List >>CA1P
CA1P
- CAS No.
- 288847-34-7
- Chemical Name:
- CA1P
- Synonyms
- CA1P;OXi-4503 sodium;Tetrasodium A1 Diphosphate;COMBRETASTATIN A-1 PHOSPHATE;TetrasodiuM coMbretastatin A1 diphosphate;Oxi 4503 Combretastatin A-1 phosphate , CA1P;CoMbretastatin A1 diphosphate tetrasodiuM salt;tetrasodium,[3-methoxy-2-phosphonooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate;3-Methoxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]-1,2-benzenediol bis(dihydrogen phosphate) tetrasodium salt
- CBNumber:
- CB72522392
- Molecular Formula:
- C18H23NaO12P2
- Molecular Weight:
- 516.31
- MDL Number:
- MFCD07368392
- MOL File:
- 288847-34-7.mol
Last updated:2023-03-31 09:12:58
CA1P price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0026173 | 3-METHOXY-6-[(Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL]-1,2-BENZENEDIOL BIS(DIHYDROGEN PHOSPHATE)TETRASODIUM 95.00% | 288847-34-7 | 10MG | $1904.79 | 2021-12-16 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| API0026173 | 10MG | $1904.79 | Buy |
CA1P Chemical Properties,Uses,Production
Description
OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue.
CA1P Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4271 | 65 | |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8147 | 55 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Shanghai ChengShao Biological Technology Co., Ltd. | 021-61847300 13341622919 | shcss01@163.com | China | 4809 | 58 |
| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 | lianshuo@vip.126.com | China | 9610 | 58 |
| Shanghai Fusheng Industrial Co., LTD | 021-52961053 13524666654 | 3004902811@qq.com | China | 9724 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31163 | 58 |
TetrasodiuM coMbretastatin A1 diphosphate
Tetrasodium A1 Diphosphate
CA1P
Oxi 4503 Combretastatin A-1 phosphate , CA1P
COMBRETASTATIN A-1 PHOSPHATE
CoMbretastatin A1 diphosphate tetrasodiuM salt
OXi-4503 sodium
3-Methoxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]-1,2-benzenediol bis(dihydrogen phosphate) tetrasodium salt
tetrasodium,[3-methoxy-2-phosphonooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate
288847-34-7
C18H18O12P2Na4