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HS-PEG4-CH2CH2COOH

HS-PEG4-CH2CH2COOH structure

CAS No.: 749247-06-1

Chemical Name:: HS-PEG4-CH2CH2COOH

Synonyms: HS-PEG4-COOH;SH-PEG4-COOH;Thiol-PEG4-acid;Thiol-PEG5-acid;Thiol-dPEG 4 acid;HS-PEG-COOH(PEG)4;Thiol-dPEG??-acid;HS-PEG4-CH2CH2COOH;HS-PEG?-CH?CH?COOH;Thiol-PEG4-propionic acid

CBNumber:: CB72546907

Molecular Formula:: C11H22O6S

Molecular Weight:: 282.35

MDL Number:: MFCD11041132

MOL File:: 749247-06-1.mol

Last updated:2025-04-18 09:52:37

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HS-PEG4-CH2CH2COOH Properties

Boiling point	422.9±45.0 °C(Predicted)
Density	1.156±0.06 g/cm3(Predicted)
storage temp.	-20°C
pka	4.28±0.10(Predicted)
form	Liquid
color	Colorless to light yellow
UNSPSC Code	12352106
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P362-P403+P233-P405-P501
HS Code	2930909899

HS-PEG4-CH2CH2COOH price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
dPEG	10247	Thiol-dPEG®₄-acid	749247-06-1	100mg	$200	2021-12-16	Buy
dPEG	10850	Thiol-dPEG®₁₂-acid	749247-06-1	100mg	$250	2021-12-16	Buy
AK Scientific	0464AP	HS-PEG4-CH2CH2COOH	749247-06-1	250mg	$291	2021-12-16	Buy
American Custom Chemicals Corporation	POL0002292	HS-DPEG-(4)-COOH 95.00%	749247-06-1	100MG	$341.25	2021-12-16	Buy
Iris Biotech GmbH	PEG1970	HS-dPEG(4)-COOH	749247-06-1	100mg	$432	2021-12-16	Buy

Product number	Packaging	Price	Buy
10247	100mg	$200	Buy
10850	100mg	$250	Buy
0464AP	250mg	$291	Buy
POL0002292	100MG	$341.25	Buy
PEG1970	100mg	$432	Buy

HS-PEG4-CH2CH2COOH Chemical Properties,Uses,Production

Description

Thiol-PEG4-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

HS-PEG4-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

HS-PEG4-CH2CH2COOH Suppliers

Global( 74)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
9i LLC	+18039569191	MWan@NiNeiLab.com	United States	418	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29808	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38630	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
9i LLC	58
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
Nextpeptide Inc	58
TargetMol Chemicals Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Xian confluore Biological Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from HS-PEG4-CH2CH2COOH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-10-24	Thiol-PEG4-acid 749247-06-1	US $0.00 / mg			10g	TargetMol Chemicals Inc.
2024-03-27	Thiol-PEG4-acid 749247-06-1	US $0.00 / g	1g	>98.00%	1g	Xian confluore Biological Technology Co., Ltd.
2020-01-10	HS-PEG4-CH2CH2COOH 749247-06-1	US $1.00 / g	1g	99.0%	100kg	Career Henan Chemical Co

Thiol-PEG4-acid
749247-06-1
US $0.00 / mg
TargetMol Chemicals Inc.

Thiol-PEG4-acid
749247-06-1
US $0.00 / g
>98.00%
Xian confluore Biological Technology Co., Ltd.

HS-PEG4-CH2CH2COOH
749247-06-1
US $1.00 / g
99.0%
Career Henan Chemical Co

749247-06-1(HS-PEG4-CH2CH2COOH)Related Search:

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1of4

HS-PEG4-CH2CH2COOH SH-PEG4-COOH Thiol-dPEG 4 acid Propanoicacid, 3-[2-[2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy]ethoxy]- HS-PEG₄-CH₂CH₂COOH Thiol-PEG4-acid 1-Mercapto-3,6,9,12-tetraoxapentadecan-15-oic acid Thiol-PEG5-acid Thiol-PEG4-propionic acid 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoic acid HS-PEG4-COOH HS-PEG-COOH(PEG)4 Thiol-dPEG??-acid HS-PEG?-CH?CH?COOH 4,7,10,13-Tetraoxapentadecanoic acid, 15-mercapto- Thiol-dPEG??-acid (QBD-10247) 749247-06-1 peg