N3-PEG4-tBu
- CAS No.
- 581066-04-8
- Chemical Name:
- N3-PEG4-tBu
- Synonyms
- N3-PEG4-tBu;N3-PEG4-tBul;Azido-PEG4-Boc;Azido-PEG4-COOtBu;N3-PEG4-CH2CH2COOtBu;Azido-PEG4-tBu Ester;Azido-PEG4-tButly ester;Azido-PEG4-CH2CH2COOtBu;N3-?PEG4-?t-?butyl ester;Azido-PEG5-t-butyl ester
- CBNumber:
- CB72546987
- Molecular Formula:
- C15H29N3O6
- Molecular Weight:
- 347.40726
- MDL Number:
- MFCD18916988
- MOL File:
- 581066-04-8.mol
N3-PEG4-tBu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-20436 | Azido-PEG4-t-butylester 98% | 581066-04-8 | 1g | $490 | 2021-12-16 | Buy |
| ChemPep | 280702 | N3-PEG4-tBu | 581066-04-8 | 1g | $493 | 2021-12-16 | Buy |
| Activate Scientific | AS103966 | N3-PEG4-CH2CH2COOtBu 95+% | 581066-04-8 | 1g | $532 | 2021-12-16 | Buy |
| BroadPharm | BP-20436 | Azido-PEG4-t-butylester 98% | 581066-04-8 | 5G | $1150 | 2021-12-16 | Buy |
| chempep | 280702 | N3-PEG4-tBu >=95% | 581066-04-8 | 5g | $1175 | 2021-12-16 | Buy |
N3-PEG4-tBu Chemical Properties,Uses,Production
Description
Azido-PEG4-t-butyl ester is a click chemistry linker containing an azide (N3) and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive toward alkyne, BCN, DBCO via Click Chemistry . The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N3-PEG4-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 3954 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
View Lastest Price from N3-PEG4-tBu manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-24 | azido-PEG4-t-Butyl ester
581066-04-8
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
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- azido-PEG4-t-Butyl ester
581066-04-8
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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