ChemicalBook >> CAS DataBase List >>Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
- CAS No.
- 168682-53-9
- Chemical Name:
- Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
- Synonyms
- CS-1110;Ezatiostat;Terrapin 199;Ezatiostat, >96%;Ezatiostat, >=98%;TER199(free base);Ezatiostat (TER199);Ezatiostat salt free;Ezatiostat 168682-53-9;Ezatiostat TFA (free base)
- CBNumber:
- CB72563432
- Molecular Formula:
- C27H35N3O6S
- Molecular Weight:
- 529.65
- MDL Number:
- MFCD27982957
- MOL File:
- 168682-53-9.mol
Last updated:2023-04-23 13:52:06
Melting point | >94°C (dec.) |
---|---|
Boiling point | 749.7±60.0 °C(Predicted) |
Density | 1.216±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 12?+-.0.46(Predicted) |
form | Solid |
color | White to Off-White |
FDA UNII | 057D10I8S8 |
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 16248 | Ezatiostat ≥98% | 168682-53-9 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 16248 | Ezatiostat ≥98% | 168682-53-9 | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 16248 | Ezatiostat ≥98% | 168682-53-9 | 10mg | $199 | 2024-03-01 | Buy |
Cayman Chemical | 16248 | Ezatiostat ≥98% | 168682-53-9 | 25mg | $442 | 2024-03-01 | Buy |
TRC | E974000 | Ezatiostat | 168682-53-9 | 5mg | $80 | 2021-12-16 | Buy |
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Chemical Properties,Uses,Production
Description
Ezatiostat is an inhibitor of glutathione S-transferase pi 1-1 (GSTP1-1; Ki = 0.4 μM). It is selective for GSTP1-1 over GSTα and GSTμ family GSTs (Kis = 20-75 μM). Ezatiostat also inhibits the protein-protein interaction between GSTP1-1 and JNK1. In vivo, ezatiostat (75 mg/kg) increases the number of circulating white blood cells in Gstp1 wild-type, but not Gstp1-/-, mice.
Uses
Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1, the most prevalent Glutathione S-transferases (GST) isozyme in nonhepatic tissues, catalytic activity with minimal effect on the related GSTα and -μ families.
target
Gutathione S-transferase
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 86)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2534 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29821 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3581 | 58 |
View Lastest Price from Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-14 | Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
168682-53-9
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
- Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
168682-53-9
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
(S)-ETHYL 2-AMINO-5-((R)-3-(BENZYLTHIO)-1-((R)-2-ETHOXY-2-OXO-1-PHENYLETHYLAMINO)-1-OXOPROPAN-2-YLAMINO)-5-OXOPENTANOATE
(2R)-L-gamma-Glutamyl-S-(phenylmethyl)-L-cysteinyl-2-phenylglycine 1,3-diethyl ester
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
Ezatiostat
Terrapin 199
Ezatiostat, >=98%
Ezatiostat, >96%
CS-1110
TER 199; TLK-199; TELINTRA
Ezatiostat (TER199)
Ezatiostat TFA (free base)
TER199(free base)
Glycine, L-γ-glutamyl-S-(phenylmethyl)-L-cysteinyl-2-phenyl-, 1,3-diethyl ester, (2R)-
Ethyl N5-((R)-3-(benzylthio)-1-(((R)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)-L-glutaminate
Ezatiostat salt free
Ezatiostat 168682-53-9
168682-53-9
C27H35N3O6S