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N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide structure

CAS No.: 1338247-35-0

Chemical Name:: N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide

Synonyms: LIMKI-3;CS-2190;BMS 5;BMS5;BMS-5 ≥95%;BMS-5， LIMKI-3;LIMKI-3;BMS5;BMS 5;LIMKI3;LIMKI 3;LIMKi3,inhibit,LIM Kinase (LIMK),LIMKs,Inhibitor,BMS 5,BMS-5,LIMKi-3;N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide;N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide[BMS5;N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide

CBNumber:: CB72598623

Molecular Formula:: C17H14Cl2F2N4OS

Molecular Weight:: 431.29

MDL Number:: MFCD17019327

MOL File:: 1338247-35-0.mol

Last updated:2024-11-19 23:02:33

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N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Properties

Density	1.54±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO:PBS (pH 7.2) (1:5):0.2(Max Conc. mg/mL);0.46(Max Conc. mM) Ethanol:3.0(Max Conc. mg/mL);6.96(Max Conc. mM)
pka	9.51±0.50(Predicted)
form	White powder.
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H312-H332
Precautionary statements	P280

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	435930	LIM Kinase Inhibitor I, LIMKi 3 - Calbiochem The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.	1338247-35-0	10MG	$259	2022-05-15	Buy
Cayman Chemical	21072	BMS-5 ≥98%	1338247-35-0	1mg	$48	2024-03-01	Buy
Cayman Chemical	21072	BMS-5 ≥98%	1338247-35-0	5mg	$152	2024-03-01	Buy
Cayman Chemical	21072	BMS-5 ≥98%	1338247-35-0	10mg	$232	2024-03-01	Buy
Tocris	4745	LIMKi3 ≥98%(HPLC)	1338247-35-0	10	$227	2021-12-16	Buy

Product number	Packaging	Price	Buy
435930	10MG	$259	Buy
21072	1mg	$48	Buy
21072	5mg	$152	Buy
21072	10mg	$232	Buy
4745	10	$227	Buy

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Chemical Properties,Uses,Production

Uses

LIMKi 3 is a LIM kinase 1 (LIMK1) inhibitor that has antitumor properties.

Definition

ChEBI: LimKi 3 is a member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2. It has a role as a LIM kinase inhibitor. It is a member of pyrazoles, a member of 1,3-thiazoles, a dichlorobenzene, an organofluorine compound and a secondary carboxamide.

storage

Store at +4°C

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Suppliers

Global( 72)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38632	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	BMS-5 1338247-35-0	US $36.00-76.00 / mg		99.88%	10g	TargetMol Chemicals Inc.
	2020-01-02	Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide 1338247-35-0	US $1.00 / KG	1KG	Min98% HPLC	g/kg/ton	Career Henan Chemical Co

BMS-5
1338247-35-0
US $36.00-76.00 / mg
99.88%
TargetMol Chemicals Inc.

Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide
1338247-35-0
US $1.00 / KG
Min98% HPLC
Career Henan Chemical Co

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide LIMKI-3 Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide BMS-5， LIMKI-3 CS-2190 BMS-5 ≥95% BMS 5;BMS5 N-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide LIMKI-3;BMS5;BMS 5;LIMKI3;LIMKI 3 Propanamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methyl- N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide[BMS5 LIMKi3,inhibit,LIM Kinase (LIMK),LIMKs,Inhibitor,BMS 5,BMS-5,LIMKi-3 1338247-35-0 C17H14Cl2F2N4OS