ANTI-HUMAN COMPLEMENT C3

CAS No.
Chemical Name:
ANTI-HUMAN COMPLEMENT C3
Synonyms
ANTI-C3C;ANTI-HUMAN C3;ANTI-C3, NEPH;ANTI-C3, HUMAN;ANTI-C3C, HUMAN;ANTI-C3A (HUMAN);ANTI-COMPLEMENT C3;ANTI-COMPLEMENT C3C;ANTI HUMAN C3, SHEEP;ANTI-C3, HUMAN (GOAT)
CBNumber:
CB7261123
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00162189
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

ANTI-HUMAN COMPLEMENT C3 Properties

storage temp. -20°C
form lyophilized powder

SAFETY

Risk and Safety Statements

WGK Germany  3

ANTI-HUMAN COMPLEMENT C3 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich GW20073F Anti-Complement C3 antibody produced in chicken affinity isolated antibody, buffered aqueous solution 50μG $362 2023-06-20 Buy
American Custom Chemicals Corporation ATB0010651 ANTI-COMPLEMENT C3 95.00% 5MG $499.91 2021-12-16 Buy
Product number Packaging Price Buy
GW20073F 50μG $362 Buy
ATB0010651 5MG $499.91 Buy

ANTI-HUMAN COMPLEMENT C3 Chemical Properties,Uses,Production

Uses

Anti-complement C3 antibody produced in chicken has been used in immunoblot analysis.

General Description

The complement factor 3 (C3) gene, with 41 exons spanning 41kb on genomic DNA, is mapped to human chromosome 19p13.3. It is the third component of complement and is characterized with α and β chains. It is one of the most abundant complement protein in the serum.

Biochem/physiol Actions

Complement factor 3 (C3) plays an essential role in the activation of the complement system. C3-convertase (C4b2a) cleaves C3 complement into C3a and C3b. C3b can bind covalently, through its reactive thioester, to cell surface carbohydrates or immune complexes and involve in the self-activation loop of complement activation via the alternate pathway. In addition, C3b also interacts with C3 convertases (C4b2a or C3bBb) to form the C5 convertase, which cleaves complement factor 5 into C5a and C5b. Derived from proteolytic degradation of complement C3, C3a (anaphylatoxin) facilitates the recruitment of inflammatory cells. C3a stimulates smooth muscle contraction, enhances vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Mutation in C3 gene leads to the development of age-related macular degeneration (AMD).

ANTI-HUMAN COMPLEMENT C3 Preparation Products And Raw materials

Raw materials

Preparation Products

ANTI-HUMAN COMPLEMENT C3 Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Supplier Advantage
Sigma-Aldrich 80
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