1-(1-Benzothiophen-4-yl)piperazine hydrochloride
- CAS No.
- 913614-18-3
- Chemical Name:
- 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
- Synonyms
- 1-(benzo[b]thiophen-4-yl)piperazine hydrochloride;1-Benzo[b]thien-4-yl-piperazine hydrochloride;7-(4-chlorobutoxy)-1-(4-chlorobutyl)quinolin-2(1H)-one;1-Benzo[b]thien-4-ylpiperazine Monohydrochloride;1-benzo[b]thien-4-yl-;Brexpiprazole intermediate;Brexpiprazole Intermediate 2;Brexpiprazole Impurity 9 HCl;Brexpiprazole Impurity 32 HCl;1-benzo[b]thien-4-yl-, hydrochloride
- CBNumber:
- CB72662777
- Molecular Formula:
- C12H15ClN2S
- Molecular Weight:
- 254.7789
- MDL Number:
- MFCD26743820
- MOL File:
- 913614-18-3.mol
- MSDS File:
- SDS
1-(1-Benzothiophen-4-yl)piperazine hydrochloride price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B194840 | 1-Benzo[b]thien-4-yl-piperazineMonohydrochloride | 913614-18-3 | 5g | $250 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB139272 | 1-Benzo[b]thien-4-ylpiperazine monohydrochloride | 913614-18-3 | 25g | $250 | 2021-12-16 | Buy |
Apolloscientific | OR305616 | 1-(1-Benzothiophen-4-yl)piperazinehydrochloride | 913614-18-3 | 5g | $116 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB139272 | 1-Benzo[b]thien-4-ylpiperazine monohydrochloride | 913614-18-3 | 10g | $125 | 2021-12-16 | Buy |
AK Scientific | V9468 | 1-(Benzo[b]thiophen-4-yl)piperazinehydrochloride | 913614-18-3 | 25g | $161 | 2021-12-16 | Buy |
1-(1-Benzothiophen-4-yl)piperazine hydrochloride Chemical Properties,Uses,Production
Uses
4-Piperazinylbenzothiophene hydrochloride is the raw material for preparing piperazine-substituted benzothiophene, which can be used for the treatment and prevention of mental diseases including central nervous system diseases.
Synthesis
Synthesis of 4-(1-piperazinyl)benzo[b]thiophene hydrochloride 4-Chlorobenzo[b]thiophene (5.00 g), piperazine (5.11 g), palladium acetate (II) (2.7 mg), tri-tert-butylphosphonium tetraphenylborate (6.2 mg), sodium tert-butoxide (8.548 g), and xylene (70 ml) were stirred at 120 to 130°C for 5 hours. After the reaction mixture was cooled to room temperature, water was added thereto, and the layers were separated. The xylene layer was washed with water, and then with saline. After addition of activated carbon, the mixture was stirred at room temperature for 30 minutes. After filtration of the mixture, concentrated hydrochloric acid was added to the filtrate, and the resulting mixture was stirred at room temperature for 30 minutes. The precipitated crystals were collected by filtration and dried to obtain compound. Yield: 6.94 g. 1H-NMR (DMSO-d6) δ ppm; 3.30 (4H, br.s), 3.61 (4H, br.s), 6.97 (1H, d, J = 7.8 Hz), 7.32 (1H, br. dd, J = 8.4, 7.8 Hz), 7.53 (1H, d, J = 5.6 Hz), 7.70 (1H, d, J = 8.4 Hz), 7.76 (1H, d, J = 5.6 Hz), 9.37 (1H, br.s).
1-(1-Benzothiophen-4-yl)piperazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9087 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
View Lastest Price from 1-(1-Benzothiophen-4-yl)piperazine hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-23 | 1-Benzo[b]thien-4-ylpiperazine monohydrochloride
913614-18-3
|
US $0.00 / Kg/Drum | 10g | 99% | 100mt/year | Jinan Finer Chemical Co., Ltd | ||
2024-03-29 | 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
913614-18-3
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd | ||
2024-03-23 | 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
913614-18-3
|
US $35.00-0.90 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
- 1-Benzo[b]thien-4-ylpiperazine monohydrochloride
913614-18-3
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
- 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
913614-18-3
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
- 1-(1-Benzothiophen-4-yl)piperazine hydrochloride
913614-18-3
- US $35.00-0.90 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
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