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Walrycin B

Walrycin B structure

CAS No.: 878419-78-4

Chemical Name:: Walrycin B

Synonyms: CS-1490;Walrycin B;Walrycin B, >95%;Walrycin B, >=98%;Bacterial,inhibit,Antibiotic,Walrycin B,Inhibitor;1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione;1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione;Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]-;1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione Walrycin B;Walrycin B 1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione

CBNumber:: CB72668517

Molecular Formula:: C14H10F3N5O2

Molecular Weight:: 337.26

MDL Number:: MFCD07188899

MOL File:: 878419-78-4.mol

Last updated:2024-11-19 20:33:22

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Walrycin B Properties

Boiling point	383.1±52.0 °C(Predicted)
Density	1.56±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	≥33.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form	solid
pka	-2.97±0.20(Predicted)
color	Yellow to orange

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Walrycin B price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21566	Walrycin B ≥98%	878419-78-4	1mg	$37	2024-03-01	Buy
Cayman Chemical	21566	Walrycin B ≥98%	878419-78-4	5mg	$116	2024-03-01	Buy
Cayman Chemical	21566	Walrycin B ≥98%	878419-78-4	10mg	$142	2024-03-01	Buy
Cayman Chemical	21566	Walrycin B ≥98%	878419-78-4	25mg	$266	2024-03-01	Buy
ApexBio Technology	B3291	WalrycinB	878419-78-4	50mg	$450	2021-12-16	Buy

Product number	Packaging	Price	Buy
21566	1mg	$37	Buy
21566	5mg	$116	Buy
21566	10mg	$142	Buy
21566	25mg	$266	Buy
B3291	50mg	$450	Buy

Walrycin B Chemical Properties,Uses,Production

Biological Activity

walrycin b is an inhibitor of walr [1].walrycin b is screened out from a chemical library. it is proved to be a selective walr inhibitor by measuring egfp fluorescence intensity. in this assay, it is found to strongly increase fluorescence intensity in strain jm109/pfi014 but has no significant effect on the strain jm109/pfi001. walrycin b shows effects on the expression of walr regulon genes in the in vivo assay. the addition of it lowers the expression of ydjm, yoch and yvce and increases the expression of yoeb and yjea rapidly. these effects caused by walrycin b are opposite with which caused by walr suggesting that walrycin b specifically affects the walk/walr system. since walk/walr plays a regulating role in cell wall metabolism and cell division in bacillus subtilis and staphylococcus aureus, walrycin b is found to cause cell death in both of them with strong mics through targeting walr [1].

References

[1] gotoh y, doi a, furuta e, dubrac s, ishizaki y, okada m, igarashi m, misawa n, yoshikawa h, okajima t, msadek t, utsumi r. novel antibacterial compounds specifically targeting the essential walr response regulator. j antibiot (tokyo). 2010 mar;63(3):127-34.

Walrycin B Preparation Products And Raw materials

Raw materials

Preparation Products

Walrycin B Suppliers

Global( 68)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7552	61
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4861	58
CEG Chemical Science&Technology Co., Ltd.	Mobile:13665161512		China	1785	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Haoyuan Chemexpress Co., Ltd.	61
MedChemexpress LLC	58
CEG Chemical Science&Technology Co., Ltd.	58

View Lastest Price from Walrycin B manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Walrycin B 878419-78-4	US $34.00-122.00 / mg		99.16%	10g	TargetMol Chemicals Inc.

Walrycin B
878419-78-4
US $34.00-122.00 / mg
99.16%
TargetMol Chemicals Inc.

Walrycin B Spectrum

Walrycin B(878419-78-4)¹HNMR

Walrycin B 1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione 1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione Walrycin B Walrycin B 1,6-Dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione Walrycin B, >=98% CS-1490 Walrycin B, >95% 1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]- Bacterial,inhibit,Antibiotic,Walrycin B,Inhibitor 878419-78-4 C14H10F3N5O2 Inhibitors