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MilbeMycin A3 OxiMe

CAS No.
114177-14-9
Chemical Name:
MilbeMycin A3 OxiMe
Synonyms
MilbeMycin A3 OxiMe;Milbemite Impurity 2;5-OxoMilbeMycin A3 oxiMe;5-ketomilbemycin A3 5-oxime;Milbemycin Impurity 10(Milbemycin A3 Oxime);Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-
CBNumber:
CB72674901
Molecular Formula:
C31H43NO7
Molecular Weight:
541.68
MDL Number:
MFCD21363714
MOL File:
114177-14-9.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

MilbeMycin A3 OxiMe Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form A crystalline solid
FDA UNII 053YPP1I9C

MilbeMycin A3 OxiMe price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27967 Milbemycin A3 oxime 114177-14-9 1mg $242 2024-03-01 Buy
Cayman Chemical 27967 Milbemycin A3 oxime 114177-14-9 5mg $965 2024-03-01 Buy
TRC M344298 MilbemycinA3oxime 114177-14-9 2.5mg $475 2021-12-16 Buy
Product number Packaging Price Buy
27967 1mg $242 Buy
27967 5mg $965 Buy
M344298 2.5mg $475 Buy

MilbeMycin A3 OxiMe Chemical Properties,Uses,Production

Description

Milbemycin A3 oxime is an anthelmintic, a derivative of milbemycin A3 , and a component of milbemycin oxide . It reduces the number of microfilariae of the heartworm D. immitis in the blood of naturally infested dogs by 85.2% when administered at a dose of 0.05 mg/kg. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs.

Uses

Milbemycin A3 oxime is the minor component of the anti-parasitic product milbemycin oxime.

Uses

Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.

MilbeMycin A3 OxiMe Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
MilbeMycin A3 OxiMe 5-OxoMilbeMycin A3 oxiMe Milbemycin Impurity 10(Milbemycin A3 Oxime) 5-ketomilbemycin A3 5-oxime Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)- Milbemite Impurity 2 114177-14-9