ChemicalBook >> CAS DataBase List >>2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- structure

CAS No.: 1564266-54-1

Chemical Name:: 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-

Synonyms: Saxagliptin Impurity 28;(1R,3R,5R)-2-Boc-3-carbamoyl-2-azabicyclo[3.1.0]hexane;(1R, 3R, 5R) -3-(aminocarbonyl) -2-aza bicyclic [3.1.0] hexane-2-tert-butyl formate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-

CBNumber:: CB72723034

Molecular Formula:: C11H18N2O3

Molecular Weight:: 226.27

MDL Number:: MFCD31743235

MOL File:: 1564266-54-1.mol

Last updated:2023-05-15 10:43:24

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2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Properties

Boiling point	388.9±21.0 °C(Predicted)
Density	1.228±0.06 g/cm3(Predicted)
pka	16.00±0.20(Predicted)

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B692930	tert-Butyl(1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate	1564266-54-1	50mg	$1230	2021-12-16	Buy

Product number	Packaging	Price	Buy
B692930	50mg	$1230	Buy

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Chemical Properties,Uses,Production

Uses

tert-Butyl (1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of (2’R,2R,cis)-Saxagliptin (S143475), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	sales1@artkmedchem.com	China	39009	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17995	56
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8864	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	2853117764@qq.com	China	8055	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
PharmaBlock Sciences (Nanjing), Inc.	025-86918232 4000255188	sales_china@pharmablock.com	China	9792	58
HX Pharmaceutical technology co., LTD	15671363360	494267389@qq.com	China	2808	58
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	SY06@accelachem.com	China	10313	58

Supplier	Advantage
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Suzhou ARTK Medchem Co., Ltd.	58
ChemStrong Scientific Co.,Ltd	56
Meng Cheng Technology (Shanghai) Co., LTD	58
Hubei Xinyang Medical Technology Co., Ltd	58
Energy Chemical	58
PharmaBlock Sciences (Nanjing), Inc.	58
HX Pharmaceutical technology co., LTD	58
Accela ChemBio Co.,Ltd.	58

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- (1R, 3R, 5R) -3-(aminocarbonyl) -2-aza bicyclic [3.1.0] hexane-2-tert-butyl formate Saxagliptin Impurity 28 (1R,3R,5R)-2-Boc-3-carbamoyl-2-azabicyclo[3.1.0]hexane 1564266-54-1