TRYPSINOGEN
- CAS No.
- 9002-08-8
- Chemical Name:
- TRYPSINOGEN
- Synonyms
- TRYPSINOGEN;Ttrypsinogen;TRYPSINOGEN FROM BEEF PANCREAS;trypsinogen from bovine pancreas;Trypsinogen >2500 U/mg from bovine;Trypsinogen >2500U/mg from bovine pancreas;Trypsinogen, PMSF treated from bovine pancreas
- CBNumber:
- CB7282580
- Molecular Formula:
- C39H55N9O17
- Molecular Weight:
- 921.9
- MDL Number:
- MFCD00466939
- MOL File:
- 9002-08-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334 |
| Precautionary statements | P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 22-24-26-36/37 |
| WGK Germany | 3 |
| F | 10-21 |
TRYPSINOGEN price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T1143 | Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) | 9002-08-8 | 250MG | $212 | 2023-06-20 | Buy |
| Sigma-Aldrich | T9011 | Trypsinogen, PMSF treated from bovine pancreas For use as a marker in SDS-PAGE | 9002-08-8 | 1VIAL | $532 | 2023-06-20 | Buy |
| Sigma-Aldrich | T1143 | Trypsinogen from bovine pancreas essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin) | 9002-08-8 | 1G | $695 | 2023-06-20 | Buy |
TRYPSINOGEN Chemical Properties,Uses,Production
Uses
Trypsinogen from bovine pancreas is suitable for use in:
- the secondary structure analysis of proteins in H2O solution using single-pass attenuated total reflection Fourier transform infrared (ATR-FT-IR) microscopy
- tuning and calibration of electrospray ionization quadrupole time-of-flight (ESI-Q-TOF) mass spectrometer
- the secondary structure analysis of proteins by infrared (IR) spectroscopy
- SDS-PAGE as a molecular weight standard (24kDa)
General Description
Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH2 terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys131 - Ser132 resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His46 and Ser183 at the active site. The pH optimum of trypsin is 7 - 9.
Biochem/physiol Actions
Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.
TRYPSINOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
TRYPSINOGEN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4529 | 58 | |
| Beijing OKA biological technology co., LTD | 010-010-010-62971590 18548936886 | jack@oka-vip.com | China | 6897 | 58 |
| Shanghai Sig Biotechnology Co., LTD | 021-57810052 18930344717 | 2089316240@qq.com | China | 9395 | 58 |
| Wuhan Yanzhe Technology Co., Ltd | 15527250409 | wenhaotian12@163.com | China | 4495 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10007 | 58 |
| Beijing Baileisen Biotechnology Co., Ltd. | 13581502185 | joe0415zhaxi@163.com | China | 141 | 58 |