Anti-Negative differentiation regulator protein
- CAS No.
- Chemical Name:
- Anti-Negative differentiation regulator protein
- Synonyms
- Anti-EDAG-1;Anti-Hemogen;Anti-Hemopoietic gene protein;Anti-HEMGN antibody produced in rabbit;Anti-Negative differentiation regulator protein;Anti-Erythroid differentiation-associated gene protein
- CBNumber:
- CB72880353
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-Negative differentiation regulator protein price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA019606 | Anti-HEMGN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA019604 | Anti-HEMGN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA019572 | Anti-HEMGN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1 | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA019606 | Anti-HEMGN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 25μL | $282 | 2023-06-20 | Buy | |
| Sigma-Aldrich | HPA019604 | Anti-HEMGN antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 25μL | $282 | 2023-06-20 | Buy |
Anti-Negative differentiation regulator protein Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
HEMGN (Hemogen) is a hematopoietic-specific nuclear protein expressed in hematopoietic tissues. Specifically, it is expressed in the human hematopoietic tissues and cells such as adult bone marrow, CD34+ progenitor cells, and leukemia cell line K562. It is located on chromosome 9q22.
Biochem/physiol Actions
HEMGN (Hemogen) is mainly involved in the regulation of hematopoietic cell differentiation, proliferation, and apoptosis. It plays an important role in transcriptional regulation. It directly binds to the transcriptional regulators to control the apoptotic gene expression. It also plays an important role in the hematopoietic regulation. Promoter region of HEMGN directly binds to the homeobox transcription factor HOXB4 and promotes expansion of hematopoietic stem cells and hematopoietic progenitor cells. It has been reported that overexpression of HEMGN in cell lines restricts the expression for apoptosis and differentiation. Study proposes that HEMGN may play a regulatory role in acute myeloid leukemia (AML) and can be a new therapeutic target for the treatment of AML.
Anti-Negative differentiation regulator protein Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Negative differentiation regulator protein Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 292394 | 58 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |