Glycerol phenylbutyrate
- CAS No.
- 611168-24-2
- Chemical Name:
- Glycerol phenylbutyrate
- Synonyms
- Ravicti;Glycerol phenylbutryate;glyceryl tri-(4-phenylbutyrate);HPN-100;Glycerol phenylbutyrate;Hydroxy Urea Impurity 9;HPN-100(Glycerol phenylbutyrate);Glycerol phenylbutyrate, 10 mM in DMSO;Propane-1,2,3-triyl tris(4-phenylbutanoate);BENZENEBUTANOIC ACID, 1,2,3-PROPANETRIYL ESTER
- CBNumber:
- CB73049827
- Molecular Formula:
- C33H38O6
- Molecular Weight:
- 530.65
- MDL Number:
- MFCD28016960
- MOL File:
- 611168-24-2.mol
| Boiling point | 621.2±45.0 °C(Predicted) |
|---|---|
| Density | 1.131±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility |
DMSO:150.0(Max Conc. mg/mL);282.67(Max Conc. mM) Ethanol:50.0(Max Conc. mg/mL);94.22(Max Conc. mM) |
| form | Oil |
| color | Colourless |
| FDA UNII | ZH6F1VCV7B |
| ATC code | A16AX09 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H302-H315-H413 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
Glycerol phenylbutyrate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T808810 | Tri(4-phenylbutyryl)glycerol | 611168-24-2 | 25mg | $65 | 2021-12-16 | Buy |
| TRC | T808810 | Tri(4-phenylbutyryl)glycerol | 611168-24-2 | 100mg | $260 | 2021-12-16 | Buy |
| ChemScene | CS-0017499 | Glycerolphenylbutyrate 99.81% | 611168-24-2 | 10mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-0017499 | Glycerolphenylbutyrate 99.81% | 611168-24-2 | 50mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0017499 | Glycerolphenylbutyrate 99.81% | 611168-24-2 | 100mg | $180 | 2021-12-16 | Buy |
Glycerol phenylbutyrate Chemical Properties,Uses,Production
Uses
Tri(4-phenylbutyryl)glycerol is a drug that is currently under development for treatment of urea cyclic disorders (UCDs). It works by preventing the harmful buildup of ammonia in the body.
Definition
ChEBI: Glycerol phenylbutyrate is a triglyceride.
Biological Activity
Glycerol phenylbutyrate, a triacylglycerol, is a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
in vivo
Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders[1][2].
IC 50
Sigma 2 Receptor
Glycerol phenylbutyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Glycerol phenylbutyrate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from Glycerol phenylbutyrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Glycerol phenylbutyrate
611168-24-2
|
US $39.00-80.00 / mg | 99.74% | 10g | TargetMol Chemicals Inc. |
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- Glycerol phenylbutyrate
611168-24-2
- US $39.00-80.00 / mg
- 99.74%
- TargetMol Chemicals Inc.