ChemicalBook >> CAS DataBase List >>4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

CAS No.
160552-54-5
Chemical Name:
4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
Synonyms
GI138870X;GI 138870X;GI-138870X;Lamivudine EP IMP H;Lamivudine EP Impurity G;Lamivudine sulfoxide, (R)-;Lamivudine Impurity (R-sulphoxide);Lamivudine EP Impurity H / R Sulfoxide;Lamivudine Impurity 8(Lamivudine EP Impurity H);Lamivudine EP Impurity H (Lamivudine (3R)-Sulfoxide)
CBNumber:
CB73051758
Molecular Formula:
C8H11N3O4S
Molecular Weight:
245.26
MDL Number:
MFCD23104278
MOL File:
160552-54-5.mol
Last updated:2023-05-15 10:43:50

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Properties

Boiling point 601.7±65.0 °C(Predicted)
Density 1.93±0.1 g/cm3(Predicted)
solubility DMSO (Slightly, Heated), Water (Slightly, Heated, Sonicated)
form Solid
pka 13.46±0.10(Predicted)
color White to Off-White
Stability Hygroscopic
FDA UNII 3SN4QFF34D

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L172475 Lamivudine(R)-Sulfoxide 160552-54-5 10mg $180 2021-12-16 Buy
TRC L172475 Lamivudine(R)-Sulfoxide 160552-54-5 100mg $1390 2021-12-16 Buy
AvaChem 3822 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on 160552-54-5 5mg $175 2021-12-16 Buy
AvaChem 3822 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on 160552-54-5 10mg $275 2021-12-16 Buy
AvaChem 3822 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on 160552-54-5 25mg $575 2021-12-16 Buy
Product number Packaging Price Buy
L172475 10mg $180 Buy
L172475 100mg $1390 Buy
3822 5mg $175 Buy
3822 10mg $275 Buy
3822 25mg $575 Buy

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Chemical Properties,Uses,Production

Uses

Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
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Standardpharm Co. Ltd.
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TargetMol Chemicals Inc.
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CR Corporation Limited
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Hangzhou Huarong Pharm Co., Ltd.
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LEAP CHEM CO., LTD.
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Amadis Chemical Company Limited
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QUALITY CONTROL SOLUTIONS LTD.
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Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 Sales@pipitech.com China 3633 55
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14055 65
4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one-S-oxide Lamivudine EP Impurity G Lamivudine Impurity 8(Lamivudine EP Impurity H) 2(1H)-Pyrimidinone,4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI) 2(1H)-Pyrimidinone, 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone Lamivudine EP Impurity H / R Sulfoxide Lamivudine EP Impurity H (Lamivudine (3R)-Sulfoxide) Lamivudine Impurit Ⅴ:4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Lamivudine Impurity Ⅴ 4-amino-1-[(2R,3R,5S)-2-(hydro xymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one-S-oxide GI 138870X GI138870X GI-138870X Lamivudine sulfoxide, (R)- Lamivudine EP IMP H Lamivudine Impurity (R-sulphoxide) 160552-54-5 60552-55-6 24526