ChemicalBook >> CAS DataBase List >>Vadadustat
Vadadustat
- CAS No.
- 1000025-07-9
- Chemical Name:
- Vadadustat
- Synonyms
- CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;Vadadustat;PG 1016548;Vardorestat;Vadadustat 13C6;PG-1016548;AKB-6548
- CBNumber:
- CB73147387
- Molecular Formula:
- C14H11ClN2O4
- Molecular Weight:
- 306.7
- MDL Number:
- MFCD30470233
- MOL File:
- 1000025-07-9.mol
Last updated:2023-12-22 10:24:25
Melting point | 172-174°C |
---|---|
Boiling point | 674.6±55.0 °C(Predicted) |
Density | 1.461±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 4.09±0.40(Predicted) |
form | Solid |
color | Pale Beige to Light Beige |
Stability | Hygroscopic |
FDA UNII | I60W9520VV |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H373 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P260-P314-P501 |
Vadadustat price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 15295 | Vadadustat | 1000025-07-9 | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 15295 | Vadadustat | 1000025-07-9 | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 15295 | Vadadustat | 1000025-07-9 | 25mg | $239 | 2024-03-01 | Buy |
Cayman Chemical | 15295 | Vadadustat | 1000025-07-9 | 50mg | $357 | 2024-03-01 | Buy |
TRC | V849530 | Vadadustat | 1000025-07-9 | 5mg | $195 | 2021-12-16 | Buy |
Vadadustat Chemical Properties,Uses,Production
Description
Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.
Uses
Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.
Vadadustat Preparation Products And Raw materials
Raw materials
Preparation Products
Vadadustat Suppliers
Global( 90)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9250 | 55 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29821 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
Related articles
- Synthesis of Vadadustat
- Vadadustat is used as raw material of boronic acid and is prepared by coupling, substitution and hydrolysis reactions.
- Dec 22,2023
View Lastest Price from Vadadustat manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-10-08 | Vadadustat
1000025-07-9
|
US $0.00-0.00 / g | 1g | 98% | 1000kgs | Wuhan Nutra Biotechnology Co.,Ltd | ||
2020-01-09 | Vadadustat
1000025-07-9
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
- Vadadustat
1000025-07-9
- US $0.00-0.00 / g
- 98%
- Wuhan Nutra Biotechnology Co.,Ltd
- Vadadustat
1000025-07-9
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
Vadadustat
AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; VADADUSTAT
PG-1016548;AKB-6548
Vadadustat(AKB-6548/PG-1016548)
Vadadustat (AKB-6548)
AKB-6548
PG 1016548
PG1016548
PG-1016548
PG-1016548; PG1016548; PG 1016548; AKB-6548
CS-2486
Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-
Vadadustat USP/EP/BP
Vadadustat (PG-1016548
Vadadustat 13C6
Valdesta
disease,HIFs,AKB 6548,Erythropoiesis-stimulating,kidney,Inhibitor,AKB6548,inhibit,Vadadustat,HIF-PH,PG 1016548,anemia,Hypoxia-inducible factors,PG1016548,nondialysis-dependent,HIF/HIF Prolyl-Hydroxylase,chronic
Vardorestat
2-(5-(3-chlorophenyl)-3-hydroxypicolinamido)acetic acid
1000025-07-9
API