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ChemicalBook >> CAS DataBase List >>5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- Structure
5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- structure
CAS No.
330785-05-2
Chemical Name:
5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
Synonyms
Avafilimpurity5;4-Desmethoxy-4-hydroxy Avanafil;(S)-4-((3-Chloro-4-hydroxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide;5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
CBNumber:
CB73147468
Molecular Formula:
C22H24ClN7O3
Molecular Weight:
469.92
MDL Number:
MOL File:
330785-05-2.mol
Request For Quotation

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- Properties

Density 1.436±0.06 g/cm3(Predicted)
pka 8.28±0.20(Predicted)

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- Chemical Properties,Uses,Production

Uses

4-Desmethoxy-4-hydroxy Avanafil is an impurity of Avanafil (A794670). Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5225 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5056 50
Taizhou Tongxin Bio-Tech Co., Ltd 0523-18601685-898 18652728585 sales@allyrise.com China 2790 60
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Shenzhen Botel Biotechnology Co. Ltd. 0755-22202135 13316968096 1979313431@qq.com China 8619 58
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 2329783215@qq.com China 12664 58
QUALITY CONTROL SOLUTIONS LTD. 13670046396 ORDERS@QCSRM.COM China 18899 58
Molcoo Chemicals Inc. 18672515910 3001051413@qq.com China 9264 58
Supplier Advantage
China National Standard Pharmaceutical Corporation Limited 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Taizhou Tongxin Bio-Tech Co., Ltd 60
Shanghai Kewel Chemical Co., Ltd. 50
Shenzhen Botel Biotechnology Co. Ltd. 58
Jinan blalong chemical co. LTD 58
Foshan Treasure Biotechnology Co., Ltd 58
QUALITY CONTROL SOLUTIONS LTD. 58
Molcoo Chemicals Inc. 58
4-Desmethoxy-4-hydroxy Avanafil Avafilimpurity5 (S)-4-((3-Chloro-4-hydroxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide 5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-hydroxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- 330785-05-2