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Fmoc-PEG12-NHS ester

CAS No.
2227246-92-4
Chemical Name:
Fmoc-PEG12-NHS ester
Synonyms
Fmoc-NH-PEG12-NHS;Fmoc-PEG12-NHS ester;FmocNH-PEG12-NHS?ester;FmocNH-PEG12-CH2CH2COONHS;Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit;2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
CBNumber:
CB73162964
Molecular Formula:
C46H68N2O18
Molecular Weight:
937.03
MDL Number:
MFCD21363319
MOL File:
2227246-92-4.mol
Last updated:2025-04-18 09:52:39

Fmoc-PEG12-NHS ester Properties

solubility Soluble in DCM
form Viscous Liquid
color Colorless to light yellow
InChIKey HQKUPHFWWTZASE-UHFFFAOYSA-N
SMILES C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O

Fmoc-PEG12-NHS ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific BIPG1422 Fmoc-PEG12-NHS ester 2227246-92-4 100mg $623 2021-12-16 Buy
BroadPharm BP-22241 Fmoc-PEG12-NHSester 95% 2227246-92-4 500mg $650 2021-12-16 Buy
BroadPharm BP-22241 Fmoc-PEG12-NHSester 95% 2227246-92-4 1g $860 2021-12-16 Buy
Activate Scientific AS107822 FmocNH-PEG12-CH2CH2COONHS 97% 2227246-92-4 1g $969 2021-12-16 Buy
BroadPharm BP-22241 Fmoc-PEG12-NHSester 95% 2227246-92-4 2g $1290 2021-12-16 Buy
Product number Packaging Price Buy
BIPG1422 100mg $623 Buy
BP-22241 500mg $650 Buy
BP-22241 1g $860 Buy
AS107822 1g $969 Buy
BP-22241 2g $1290 Buy

Fmoc-PEG12-NHS ester Chemical Properties,Uses,Production

Description

Fmoc-PEG12-NHS ester is a PEG linker containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
Changsha Morning Shine Co., Ltd.
+8613570080128 +86-13751227286 wanglin@hanchbio.cn China 228 58
Adachibio Inc.
+8108027837258 sales@adachi-bio.com China 992 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32202 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Changsha Morning Shine Co., Ltd. 18975870350 13397510867 liyan@csmspharm.com China 289 58
Alabiochem Tech.Co., Ltd. 512-58900862 400-0707518 sales@alabiochem.com China 970 59
Chengdu Pukang Biotechnology Co., Ltd +86-028-82550498 +86-19102685862 sales@pu-kang.com China 489 58
Jinan elephant international trading co., LTD 13006575422@163.com China 6355 58

View Lastest Price from Fmoc-PEG12-NHS ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-PEG12-NHS ester pictures 2024-11-19 Fmoc-PEG12-NHS ester
2227246-92-4
US $39.00-89.00 / mg ≥98% 10g TargetMol Chemicals Inc.
FmocNH-PEG12-NHS ester pictures 2024-03-25 FmocNH-PEG12-NHS ester
2227246-92-4
US $0.00 / g 1g >99.00% 1g Xian confluore Biological Technology Co., Ltd.
Fmoc-PEG12-NHS ester FmocNH-PEG12-NHS?ester FmocNH-PEG12-CH2CH2COONHS 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester Fmoc-NH-PEG12-NHS Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester 2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate 2227246-92-4 C46H68N2O18