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(R)-1-Boc-3-Aminopiperidine

(R)-1-Boc-3-Aminopiperidine Structure
(R)-1-Boc-3-Aminopiperidine structure
CAS No.
188111-79-7
Chemical Name:
(R)-1-Boc-3-Aminopiperidine
Synonyms
tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
CBNumber:
CB7326716
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MDL Number:
MFCD03094717
MOL File:
188111-79-7.mol
MSDS File:
SDS
Last updated:2023-07-03 15:15:11
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(R)-1-Boc-3-Aminopiperidine Properties

alpha 28.5 º (c=1, DMF)
Boiling point 277.3±33.0 °C(Predicted)
Density 1.041±0.06 g/cm3(Predicted)
refractive index 1.4730
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka 10.35±0.20(Predicted)
form Liquid
color Colorless to pale yellow
optical activity [α]/D -28.5±2°, c = 1 in DMF
Water Solubility Immiscible with water.
Sensitive Moisture Sensitive
InChI InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference 188111-79-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  UN2735
WGK Germany  3
F  10-34
HazardClass  8
PackingGroup  III
HS Code  29333990
NFPA 704
1
2 0

(R)-1-Boc-3-Aminopiperidine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07858 (R)-(−)-3-Amino-1-Boc-piperidine ≥98.0% (TLC) 188111-79-7 1G-F $283 2024-03-01 Buy
Sigma-Aldrich 07858 (R)-(−)-3-Amino-1-Boc-piperidine ≥98.0% (TLC) 188111-79-7 1g $272 2023-01-07 Buy
Alfa Aesar H26937 (R)-(-)-3-Amino-1-Boc-piperidine, 98% 188111-79-7 5g $392.65 2024-03-01 Buy
TRC B692215 tert-Butyl(R)-3-Aminopiperidine-1-carboxylate 188111-79-7 1g $150 2021-12-16 Buy
Biosynth Carbosynth FA10567 (3R)-3-Amino-N1-Boc-piperidine 188111-79-7 25g $200 2021-12-16 Buy
Product number Packaging Price Buy
07858 1G-F $283 Buy
07858 1g $272 Buy
H26937 5g $392.65 Buy
B692215 1g $150 Buy
FA10567 25g $200 Buy

(R)-1-Boc-3-Aminopiperidine Chemical Properties,Uses,Production

Chemical Properties

Yellow liquid

Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Uses

(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.

General Description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

(R)-1-Boc-3-Aminopiperidine synthesis

320580-76-5
188111-79-7
Synthesis of (R)-1-Boc-3-Aminopiperidine from 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)-

(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-

Preparation Products

(R)-tert-Butyl 3-(pyridin-2-ylamino)piperidine-1-carboxylate DiMethyl-(R)-piperidin-3-yl-aMine

(R)-1-Boc-3-Aminopiperidine Suppliers

Global( 398)Suppliers
Supplier Tel Email Country ProdList Advantage
Lianhe Aigen Pharmatech Co.,Ltd.
+undefined+undefined18918657159 sales-Aigen@lianhetech.com China 314 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 9206 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
AB PharmaTech,LLC 		323-480-4688 sales@acrospharmatech.com United States 989 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2136 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
Supplier Advantage
Lianhe Aigen Pharmatech Co.,Ltd.
58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
AB PharmaTech,LLC 		55
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Shenzhen Nexconn Pharmatechs Ltd 		58

View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-1-Boc-3-Aminopiperidine pictures 2022-02-25 (R)-1-Boc-3-Aminopiperidine
188111-79-7
 US $100.00 / KG 1KG 98% 100KG Hong Kong Tiansheng New Material Trading Co., Ltd
tert-butyl (3R)-3-aminopiperidine-1-carboxylate pictures 2022-02-25 tert-butyl (3R)-3-aminopiperidine-1-carboxylate
188111-79-7
 US $100.00 / KG 1KG 98% 10KG Hong Kong Tiansheng New Material Trading Co., Ltd
(R)-1-Boc-3-Aminopiperidine pictures 2022-02-24 (R)-1-Boc-3-Aminopiperidine
188111-79-7
 US $10.00 / KG 1KG 99% 10tons Xingtai Haoxun Import and Export Trade Co., Ltd.

(R)-1-Boc-3-Aminopiperidine Spectrum

(R)-1-Boc-3-Aminopiperidine(188111-79-7)1HNMR

188111-79-7((R)-1-Boc-3-Aminopiperidine)Related Search:

Glycine Haloperidol 3-AMINOPIPERIDINE tert-Butyl carbazate N-Carbobenzyloxyglycine
tert-Butanol 6-Aminocaproic acid ALTRENOGEST Tris(hydroxymethyl)aminomethane 8-Bromo-3-methyl-xanthine
2-Aminoacetophenone (R)-Boc-Nipecotic acid Diphenoxylate 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1,1'-Diacetylferrocene
(R)-1-Boc-3-Aminopiperidine-3-carboxylic acid (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE Piperidine

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(R)-3-Aminopiperidine, N1-BOC protected (R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine 1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI) (R)-3-AMINO-N-BOC-PIPERIDINE (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL (R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE (R)-1-BOC-3-PIPERIDINAMINE (R)-1-BOC-3-AMNIOPIPERIDINE (R)-1-BOC-3-AMINOPIPERIDINE (R)-1-BOC-3-AMINOPIPERIDINE HCL (R)-1-N-BOC-3-AMINO PIPERIDINE (R)-N-BOC-3-AMINOPIPERIDINE TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE (3R)-3-Aminopiperidine, N1-BOC protected (3R)-3-Amino-N1-Boc-piperidine (R)-1-Boc-3-aMinopiperidi... (R)-1-Boc-3-AMinopiperidin tert-Butyl (3R)-3-aminopiperidine-1-carboxylate, (3R)-3-Amino-1-(tert-butoxycarbonyl)piperidine (R)-1-Boc-3-AMniopiperidine SynonyMs (R)-3-AMino-1-N-Boc-piperidine (R)-tert-Butyl 3-aMinopiperidine-1-carboxylate, >95% (R)-(-)-3-Amino-1-Boc-piperidine,98% (R)-1-Boc-3-aminopiperidine,99%e.e. 1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE 1-tert-butyloxycarbonyl-3-r-aminopiperidine 1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)- (R)-BOC-PIP(3-NH2) HCL (R)-3-AMINO-1-BOC-PIPERIDINE (R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE 2-Methyl-2-propanyl (3S)-3-amino-1-piperidinecarboxylate (R)-1-tert-butoxycarbonyl-3-aminoperidol 3-aminopiperidine-1-carboxyL Linagliptin Impurity 69 Linagliptin N-t-BOC Piperidine Impurity Linagliptin Impurity 98 (R)-3-aminopiperidine-1-carboxylate ert-butyl(3R)-3-aminopiperidine-1-carboxylate (R)-1-Boc-3-Aminopiperidine USP/EP/BP tert-Butyl (3R)-3-aminopiperidine-1-carboxylate (R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE tert-butyl (R)-3-aminopiperidine-1-carboxylate (R)-3-AMINO-1-N-BOC-PIPERIDINE LigliptinImpurity69 (R)-tert-Butyl 3-amino-piperidin-1-carboxylate 188111-79-7 1152113-32-0 1118-90-1 C10H21ClN2O2 CHIRAL CHEMICALS Piperidines Piperidine Series pharmacetical Piperidine AMINOACID