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GSK2837808A

GSK2837808A structure

CAS No.: 1445879-21-9

Chemical Name:: GSK2837808A

Synonyms: GSK2837808A;GSK 2837808A (GSK2837808A);Inhibitor,inhibit,LDH,Lactate Dehydrogenase,GSK2837808A,GSK-2837808A;3-[[3-(cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)-4-quinolyl]amino]-5-(3,5-difluorophenoxy)benzoic acid;3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid;3-[[3-[(Cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)benzoic acid;Benzoic acid, 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-

CBNumber:: CB73333612

Molecular Formula:: C31H25F2N5O7S

Molecular Weight:: 649.62

MDL Number:: MFCD28133406

MOL File:: 1445879-21-9.mol

Last updated:2024-11-19 23:02:33

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GSK2837808A Properties

Boiling point	783.5±70.0 °C(Predicted)
Density	1.57±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	crystalline solid
pka	3.81±0.10(Predicted)
color	Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

NFPA 704

	0
2		0

GSK2837808A price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20626	GSK2837808A ≥98%	1445879-21-9	1mg	$44	2024-03-01	Buy
Cayman Chemical	20626	GSK2837808A ≥98%	1445879-21-9	5mg	$183	2024-03-01	Buy
Cayman Chemical	20626	GSK2837808A ≥98%	1445879-21-9	10mg	$323	2024-03-01	Buy
Cayman Chemical	20626	GSK2837808A ≥98%	1445879-21-9	25mg	$684	2024-03-01	Buy
TRC	G797465	GSK2837808A	1445879-21-9	5mg	$360	2021-12-16	Buy

Product number	Packaging	Price	Buy
20626	1mg	$44	Buy
20626	5mg	$183	Buy
20626	10mg	$323	Buy
20626	25mg	$684	Buy
G797465	5mg	$360	Buy

GSK2837808A Chemical Properties,Uses,Production

Uses

GSK 2837808A may be lactate dehydrogenase A activity inhibitor.This compound is suitable for lactate dehydrogenase (LDH) related research.

Biological Activity

gsk2837808a is a potent, selective lactate dehydrogenase a (ldha) inhibitor (ic50 values are 1.9 and 14 nm for ldha and ldhb respectively).in snu398 but not hepg2 hepatocellular carcinoma cells. gsk2837808a (10 μm) reduces glucose consumption.after intravenous injection of gsk2837808a at 0.25 mg/kg in rats, the clearance is shown to be 69 ml/min/kg, which exceeds the blood flow of the animal liver. oral administration of gsk2837808a at 50 mg/kg or 100 mg/kg in rats or mice, respectively, resulted in blood compound levels reaching or below the detection limit of 2.5 ng/ml.[1]. billiard j, dennison j b, briand j, et al. quinoline 3-sulfonamides inhibit lactate dehydrogenase a and reverse aerobic glycolysis in cancer cells. cancer & metabolism, 2013, 1(1): 19-19.

storage

Store at -20°C

GSK2837808A Preparation Products And Raw materials

Raw materials

Preparation Products

GSK2837808A Suppliers

Global( 75)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1460	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39004	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070	info@chemlin.com.cn	China	19179	64
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65

Supplier	Advantage
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Chemtour Biotech Co., Ltd	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Nanjing Chemlin Chemical Co., Ltd	64
BOC Sciences	65

View Lastest Price from GSK2837808A manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	GSK2837808A 1445879-21-9	US $40.00-179.00 / mg		99.78%	10g	TargetMol Chemicals Inc.

GSK2837808A
1445879-21-9
US $40.00-179.00 / mg
99.78%
TargetMol Chemicals Inc.

GSK2837808A Spectrum

GSK2837808A(1445879-21-9)¹HNMR

1445879-21-9(GSK2837808A)Related Search:

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GSK-2256098 GSK215

1of4

GSK2837808A GSK 2837808A (GSK2837808A) 3-[[3-[(Cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)benzoic acid Benzoic acid, 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)- 3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid Inhibitor,inhibit,LDH,Lactate Dehydrogenase,GSK2837808A,GSK-2837808A 3-[[3-(cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)-4-quinolyl]amino]-5-(3,5-difluorophenoxy)benzoic acid 1445879-21-9 C31H25F2N5O7S