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Chloramine-T

CAS No.
127-65-1
Chemical Name:
Chloramine-T
Synonyms
CHLORAMINE T;Tosylchloramide sodium;SodiuM chloro(tosyl)aMide;halamid;chlorazan;MI 9;NF X;anexol;GANSIL;clorina
CBNumber:
CB7344990
Molecular Formula:
C7H7ClNNaO2S
Molecular Weight:
227.64
MDL Number:
MFCD00000522
MOL File:
127-65-1.mol
Last updated:2024-10-31 13:32:20

Chloramine-T Properties

Melting point 167-170 °C(lit.)
Density 1.401[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. Sealed in dry,2-8°C
solubility H2O: >100 mg/mL
pka 0.39[at 20 ℃]
form Solid
color White to off-white
Water Solubility 150g/L at 25℃
Stability Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air.
InChI InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1
InChIKey VDQQXEISLMTGAB-UHFFFAOYSA-N
SMILES S(=O)(=O)(N(Cl)[Na])C1C=CC(C)=CC=1
LogP -1.3 at 20℃
CAS DataBase Reference 127-65-1(CAS DataBase Reference)
FDA 21 CFR 556.118
Indirect Additives used in Food Contact Substances SODIUM P-TOLUENESULFONCHLOROAMIDE
EWG's Food Scores 1-6
FDA UNII 328AS34YM6
ATC code D08AX04
EPA Substance Registry System Chloramine T (127-65-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  C,Xn
Risk Statements  22-31-34-42
Safety Statements  22-26-36/37/39-45-7-1/2
RIDADR  UN 3263 8/PG 3
WGK Germany  2
HazardClass  8
PackingGroup  III
HS Code  29242990

Chloramine-T price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S470155 AKTIVIN AldrichCPR 127-65-1 1G $179 2024-03-01 Buy
Matrix Scientific 099856 Sodium chloro(tosyl)amide 95+% 127-65-1 100g $285 2021-12-16 Buy
ChemScene CS-4435 Chloramine-T ≥98.0% 127-65-1 500mg $50 2021-12-16 Buy
ChemScene CS-4435 Chloramine-T ≥98.0% 127-65-1 1g $60 2021-12-16 Buy
Matrix Scientific 099856 Sodium chloro(tosyl)amide 95+% 127-65-1 25g $118 2021-12-16 Buy
Product number Packaging Price Buy
S470155 1G $179 Buy
099856 100g $285 Buy
CS-4435 500mg $50 Buy
CS-4435 1g $60 Buy
099856 25g $118 Buy

Chloramine-T Chemical Properties,Uses,Production

Description

The sodium salt of p-toluenesulfochloramide, commonly known as chloramine-T, exerts strong oxidizing action in both acidic and alkaline media and thus has been widely used for the oxidimetric determination of a large number of inorganic and organic substances. Oxidation of some aldehydes by chloramine-T has been reported to occur quantitatively in an alkaline solution, giving the corresponding acid as the end product. Both direct and indirect methods have been carried out to estimate aldehydes by chloramine-T. Chloramine-T (CAT) is also commonly used in radiolabeling bioactive molecules by halogenation. CAT is used to release radioactive elemental iodine by oxidation of its salts. Unfortunately, CAT is a strong oxidizing agent and can cause significant damage to peptides and proteins. This may lower the yield of the iodination reaction and may produce undesirable side products[1-2]. 

Chemical Properties

white or yellow powder with a chlorine-like odour

Uses

sterilizer, antiseptic, disinfectant, and chemical reagent in the medical and pharmaceutical fields.

Uses

antiseptic, disinfestant, antiproliferative

Uses

This disinfectant is for external use only, it can exterminate bacteria, viruses, fungi, spore. The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced by Chloramine-T solution. Apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.

Definition

ChEBI: An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.

Flammability and Explosibility

Not classified

Safety Profile

Poison by parenteral and intravenous routes. Human mutagenic data reported. When heated to decomposition it emits toxic fumes of Cl-, SOx, Na2O, and NOx. See also SULFONATES and CHLORIDES.

Synthesis

Chloramine-T is prepared in 75 – 95 % yield by passing chlorine into a sodium hydroxide solution of p-toluenesulfonamide. It is a strong electrolyte in acid solution and a good oxidizing agent in base. It is fairly soluble in water, and practically insoluble in benzene, chloroform, and ether. The compound reacts readily with mustard gas to yield a harmless crystalline sulfimide; chloramine-T derivatives are being studied as protective agents against poison gas.
synthesis of Chloramine-T

References

[1] M. C. Agrawal, S. P. Mushran. "Mechanism of Oxidation of some Aliphatic Aldehydes by Chloramine-T." Zeitschrift für Naturforschung B 20 1 (1972): 401–404.
[2] B M Tashtoush. "Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques." Analytical biochemistry 288 1 (2001): 16–21.

70-55-3
127-65-1
Synthesis of Chloramine-T from p-Toluenesulfonamide
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View Lastest Price from Chloramine-T manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chloramine-T pictures 2024-11-28 Chloramine-T
127-65-1
US $5.00 / kg 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
Chloramine-T pictures 2024-11-28 Chloramine-T
127-65-1
US $40.00 / kg 1kg 99% 5000kg/Week Hebei Zhuanglai Chemical Trading Co.,Ltd
Chloramine-T pictures 2024-10-31 Chloramine-T
127-65-1
US $0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
  • Chloramine-T pictures
  • Chloramine-T
    127-65-1
  • US $5.00 / kg
  • ≥99%
  • Jinan Finer Chemical Co., Ltd
  • Chloramine-T pictures
  • Chloramine-T
    127-65-1
  • US $40.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • Chloramine-T pictures
  • Chloramine-T
    127-65-1
  • US $0.00 / KG
  • 99%
  • Hebei Weibang Biotechnology Co., Ltd
chlorazene chlorosol chlorozone chlorseptol clorina clorosan desinfect gyneclorina heliogen kloramin kloramine-t mannolite monochloraminet multichlor N-Chloro-4-methylben-zenesulfonamide n-chloro-4-methylbenzenesulfonamidesodiumsalt n-chloro-4-methyl-benzenesulfonamidsodiumsalt n-chloro-4-methylbenzylsulfonamidesodiumsalt N-Chloro-4-tolunesulfonamide,sodiumsalt n-chloro-p-toluenesulfonamidesodium n-chloro-p-toluenesulfonamidsodiumsalt n-chlorotoluenesulfonamidesodiumsalt sodiumchloraminet sodiumn-chloro-p-toluenesulfonamide sodiump-toluenesulfonylchloramide sodiumtosylchloramide tampules tochlorine tolamine tosylchloramide TN-Chloro-4-toluenesulfonaMide sodiuM salt(HALAMID) BenzenesulfonaMide,N-chloro-4-Methyl-, sodiuM salt (1:1) P-TOLUENESULFONCHLORAMIDE SODIUM SALT SODIUM-P-TOLUENESULFONCHLORAMIDE N-CHLORO-4-METHYL-BENZENESULFONAMIDE SODIUM N-CHLORO-4-TOLUENESULFONAMIDE, SODIUM SALT N-CHLORO-P-TOLUENESULPHONAMIDE, SODIUM SALT N-CHLORO-P-TOLUENESULFONAMIDE SODIUM SALT MONOCHLORAMINE REAGENT MIANINE Chloramine T (Tosyl Chloramide Sodium Salt) (n-chloro-p-toluenesulfonamido)sodium acti-chlore aktivin anexol Benzenesulfonamide,N-chloro-4-methyl-,sodiumsalt IODO-BEADS(R) GYNECHLORINA EUCLORINA GANSIL CHLORAZONE CHLORAMINE T POLYMER BOUND CHLORAMINE T SODIUM CHLORASEPTINE N-Chloro-P-Toluenesulfonamide Odium Salt ChloramineT,A.R. p-ChloramineThydrate ChloramineT,99.5%