Pinostrobin
- CAS No.
- 480-37-5
- Chemical Name:
- Pinostrobin
- Synonyms
- Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
- CBNumber:
- CB7350900
- Molecular Formula:
- C16H14O4
- Molecular Weight:
- 270.28
- MDL Number:
- MFCD06858342
- MOL File:
- 480-37-5.mol
- MSDS File:
- SDS
Melting point | 100°C |
---|---|
Boiling point | 494.9±45.0 °C(Predicted) |
Density | 1.284±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml |
form | A crystalline solid |
pka | 7.40±0.40(Predicted) |
color | White to yellow |
LogP | 3.591 (est) |
FDA UNII | SZD9LZS694 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
Pinostrobin price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 22436 | Pinostrobin ≥98% | 480-37-5 | 5mg | $38 | 2024-03-01 | Buy |
Cayman Chemical | 22436 | Pinostrobin ≥98% | 480-37-5 | 1mg | $38 | 2023-06-20 | Buy |
Cayman Chemical | 22436 | Pinostrobin ≥98% | 480-37-5 | 10mg | $72 | 2024-03-01 | Buy |
TRC | H947653 | Pinostrombin | 480-37-5 | 10mg | $1400 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP66572 | Pinostrobin | 480-37-5 | 50mg | $150 | 2021-12-16 | Buy |
Pinostrobin Chemical Properties,Uses,Production
Description
Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).
Uses
Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.
Definition
ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.
Pinostrobin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3003 | 58 |
Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10319 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
Henan Alfa Chemical Co., Ltd | China | 11415 | 58 |
View Lastest Price from Pinostrobin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-11 | Pinostrobin
480-37-5
|
US $1.00-2.10 / KG | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd | ||
2019-12-31 | Pinostrobin
480-37-5
|
US $1.00 / KG | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
- Pinostrobin
480-37-5
- US $1.00-2.10 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- Pinostrobin
480-37-5
- US $1.00 / KG
- 95-99%
- Career Henan Chemical Co