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Pinostrobin

CAS No.
480-37-5
Chemical Name:
Pinostrobin
Synonyms
Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
CBNumber:
CB7350900
Molecular Formula:
C16H14O4
Molecular Weight:
270.28
MDL Number:
MFCD06858342
MOL File:
480-37-5.mol
MSDS File:
SDS
Last updated:2024-08-11 15:28:25

Pinostrobin Properties

Melting point 100°C
Boiling point 494.9±45.0 °C(Predicted)
Density 1.284±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml
form A crystalline solid
pka 7.40±0.40(Predicted)
color White to yellow
LogP 3.591 (est)
FDA UNII SZD9LZS694

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

Pinostrobin price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 5mg $38 2024-03-01 Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 1mg $38 2023-06-20 Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 10mg $72 2024-03-01 Buy
TRC H947653 Pinostrombin 480-37-5 10mg $1400 2021-12-16 Buy
Biosynth Carbosynth FP66572 Pinostrobin 480-37-5 50mg $150 2021-12-16 Buy
Product number Packaging Price Buy
22436 5mg $38 Buy
22436 1mg $38 Buy
22436 10mg $72 Buy
H947653 10mg $1400 Buy
FP66572 50mg $150 Buy

Pinostrobin Chemical Properties,Uses,Production

Description

Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).

Uses

Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.

Definition

ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.

90-24-4
480-37-5
Synthesis of Pinostrobin from 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE
Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3003 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 953 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
BOC Sciences
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
career henan chemical co
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Wuhan ChemNorm Biotech Co.,Ltd.
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Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
Henan Alfa Chemical Co., Ltd
China 11415 58

View Lastest Price from Pinostrobin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pinostrobin pictures 2024-08-11 Pinostrobin
480-37-5
US $1.00-2.10 / KG 1KG 99% 20000KG Shaanxi Dideu Medichem Co. Ltd
	Pinostrobin pictures 2019-12-31 Pinostrobin
480-37-5
US $1.00 / KG 1KG 95-99% 1ton Career Henan Chemical Co
  • Pinostrobin pictures
  • Pinostrobin
    480-37-5
  • US $1.00-2.10 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd
  • 	Pinostrobin pictures
  • Pinostrobin
    480-37-5
  • US $1.00 / KG
  • 95-99%
  • Career Henan Chemical Co
2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one 2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one Pinostobin Pistrobin Pinostrobin,(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL) 5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one 5-Hydroxy-7-methoxyflavanone (S)-2,3-DIHYDRO-5-HYDROXY-7-METHOXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE PINOSTROBIN (S)-2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone (2S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)- Pinostrombin 5-Hydroxy-7-methoxyflavanone (Pinostrobin) 5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin loteprednol Impurity 18 480-37-5 Food Residue Analysis Food & Beverage Standards Chromatography Analytical Standards Analytical Chromatography Product Catalog Flavanones