Chinese Japanese Germany Korea

FEROTKYRPUJIEB-UHFFFAOYSA-N

FEROTKYRPUJIEB-UHFFFAOYSA-N Structure
FEROTKYRPUJIEB-UHFFFAOYSA-N structure
CAS No.
1934302-25-6
Chemical Name:
FEROTKYRPUJIEB-UHFFFAOYSA-N
Synonyms
UNC0321 TFA;FEROTKYRPUJIEB-UHFFFAOYSA-N
CBNumber:
CB73544160
Molecular Formula:
C29H46F3N7O5
Molecular Weight:
629.73
MDL Number:
MOL File:
1934302-25-6.mol
Last updated:2023-04-10 09:29:30
Request For Quotation

FEROTKYRPUJIEB-UHFFFAOYSA-N Properties

solubility DMF: 10 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 5 mg/ml

FEROTKYRPUJIEB-UHFFFAOYSA-N price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10582 UNC0321 (trifluoroacetate salt) ≥95% 1934302-25-6 1mg $47 2023-06-20 Buy
Cayman Chemical 10582 UNC0321 (trifluoroacetate salt) ≥95% 1934302-25-6 5mg $114 2023-06-20 Buy
Cayman Chemical 10582 UNC0321 (trifluoroacetate salt) ≥95% 1934302-25-6 10mg $205 2023-06-20 Buy
Cayman Chemical 10582 UNC0321 (trifluoroacetate salt) ≥95% 1934302-25-6 50mg $791 2023-06-20 Buy
Product number Packaging Price Buy
10582 1mg $47 Buy
10582 5mg $114 Buy
10582 10mg $205 Buy
10582 50mg $791 Buy

FEROTKYRPUJIEB-UHFFFAOYSA-N Chemical Properties,Uses,Production

Description

The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0321 is a potent and selective G9a HMTase inhibitor, exhibiting a Ki value of 63 pM. UNC0321 inhibits G9a with assay-dependent IC50 values of 6-9 nM and GLP, a closely-related H3K9 HMTase, with assay-dependent IC50 values of 15-23 nM. It is more than 40,000-fold selective against SET7/9 (a H3K4 HMTase), SET8 (a H4K20 HMTase), PRMT3, and JMJD2E.

FEROTKYRPUJIEB-UHFFFAOYSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

FEROTKYRPUJIEB-UHFFFAOYSA-N Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19696 58
Supplier Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
FEROTKYRPUJIEB-UHFFFAOYSA-N UNC0321 TFA 1934302-25-6