LHPURSCMUYRRRM-UHFFFAOYSA-N
- CAS No.
- 247069-93-8
- Chemical Name:
- LHPURSCMUYRRRM-UHFFFAOYSA-N
- Synonyms
- PubChem ID: 91759536;LHPURSCMUYRRRM-UHFFFAOYSA-N;BODIPY-aminoacetaldehyde diethyl acetal;N-(2,2-Diethoxyethyl)-3-(5,5-difluoro-1,3-dimethyl-3H,5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-7-yl)propanamide;N-(2,2-Diethoxyethyl)-3-(5,5-difluoro-1,3-dimethyl-3H,5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-7-yl)propanamide;(T-4)-[N-(2,2-diethoxyethyl)-5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-kN)methyl]-1H-pyrrole-2-propanamidato-κN1]difluoro-boron
- CBNumber:
- CB73574563
- Molecular Formula:
- C20H28BF2N3O3
- Molecular Weight:
- 407.2624264
- MDL Number:
- MFCD28400782
- MOL File:
- 247069-93-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
LHPURSCMUYRRRM-UHFFFAOYSA-N price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 9002056 | BODIPY-aminoacetaldehyde diethyl acetal | 247069-93-8 | 50μg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 9002056 | BODIPY-aminoacetaldehyde diethyl acetal | 247069-93-8 | 1mg | $1003 | 2024-03-01 | Buy |
| Cayman Chemical | 9002056 | BODIPY-aminoacetaldehyde diethyl acetal | 247069-93-8 | 100μg | $138 | 2024-03-01 | Buy |
| Cayman Chemical | 9002056 | BODIPY-aminoacetaldehyde diethyl acetal | 247069-93-8 | 500μg | $575 | 2024-03-01 | Buy |
| AK Scientific | 1377EC | BODIPY-aminoacetaldehydediethylacetal | 247069-93-8 | 1mg | $1215 | 2021-12-16 | Buy |
LHPURSCMUYRRRM-UHFFFAOYSA-N Chemical Properties,Uses,Production
Biological Activity
BODIPY-aminoacetaldehyde diethyl acetal (BAAA-DA) is a stable precursor to BODIPY-aminoacetaldehyde, a cell-permeable fluorescent substrate for aldehyde dehydrogenase (ALDH).1,2 BODIPY-aminoacetaldehyde diethyl acetal is converted under acidic conditions to BODIPY-aminoacetaldehyde (BAAA).2 BAAA is cell-permeant and is converted intracellularly by ALDH to BODIPY aminoacetate (BAA), which is retained by cells and can be used to identify cells with high ALDH activity.1 BAA is a substrate for the efflux pump P-glycoprotein (P-gp) but co-application of BAAA with a P-gp inhibitor, such as verapamil , inhibits BAA efflux.2 BAAA-DA has been used to isolate human hematopoietic progenitor cells, which have high ALDH activity, and via flow cytometry to sort cancer stem cells that contain high levels of ALDH.1,3 BAA used in cells can be excited at 488 nm and displays an emission maximum of 512 nm.4
References
1.Storms, R.W., Trujillo, A.P., Springer, J.B., et al.Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activityProceedings of the National Academy of Sciences of the United States of America96(16)9118-9123(1999) 2.Smith, C.A., Colvin, M., Storms, R.W., et al.BODIPY aminoacetaldehyde diethyl acetal08010501.81-15(2010) 3.Leng, Z., Yang, Z., Li, L., et al.A reliable method for the sorting and identification of ALDHhigh cancer stem cells by flow cytometryExp. Ther. Med.(2017) 4.Pomper, M.G., Wang, H., Minn, I., et al.Red fluorescent aldehyde dehydrogenase (ALDH) substrate(2015)
LHPURSCMUYRRRM-UHFFFAOYSA-N Preparation Products And Raw materials
Raw materials
Preparation Products
LHPURSCMUYRRRM-UHFFFAOYSA-N Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan's chemical products co., LTD | 0371-60919097 15378766539 | 794449696@qq.com | China | 4976 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-0371-55055611 18137792234 | 3002694073@qq.com | China | 10245 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 | sales@ubiochem.com | China | 4297 | 58 |
| Anqing Donghe Biotechnology Co., Ltd | 15056029383 | product@aqdonghe.com | China | 1508 | 58 |
| ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
| Shanghai Annengjian Biomedical Technology Co., LTD | 021-68781987 13818305065 | sales@energybiopharma.com | China | 285 | 58 |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | sales@szzxbio.com | China | 3014 | 58 |
| Henan Dowon Chemical Technology Co., Ltd. | 16696119288 | 779113375@qq.com | China | 7309 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
| Shaanxi Istare Biotechnology Co., Ltd. | 18682931470 | 2142355700@qq.com | China | 3060 | 58 |