ChemicalBook >> CAS DataBase List >>Naloxone hydrochloride dihydrate
Naloxone hydrochloride dihydrate
- CAS No.
- 51481-60-8
- Chemical Name:
- Naloxone hydrochloride dihydrate
- Synonyms
- NaloxonHCl-Dihydrat;Naloxone HCl dihydrate;NaloxonhydrochloridDihydrat;naloxone F&D version of N7758;loxone hydrochloride dihydrate;NALOXONE HYDROCHLORIDE, DIHYDRATE;Naloxone dihydrate hydrochloride;NALOXONEHYDROCHLORIDE,DIHYDRATE,USP;Naloxone hydrochloride dihydrate CRS;Naloxone for peak identification CRS
- CBNumber:
- CB7409260
- Molecular Formula:
- C19H26ClNO6
- Molecular Weight:
- 399.87
- MDL Number:
- MFCD00150901
- MOL File:
- 51481-60-8.mol
Last updated:2023-04-23 13:52:06
| Melting point | 182 °C (dec.)(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | ethanol: 3.3 mg/mL stable for several months refrigerated if protected from light. |
| form | powder |
| color | white to off-white |
| optical activity | [α]25/D 178.6°, c = 2.5 in H2O(lit.) |
| Merck | 13,6388 |
| BRN | 6260807 |
| CAS DataBase Reference | 51481-60-8(CAS DataBase Reference) |
| FDA UNII | 5Q187997EE |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-26-36/37/39-36 |
| WGK Germany | 3 |
Naloxone hydrochloride dihydrate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N7758 | Naloxone hydrochloride dihydrate ≥98% (TLC and titration), powder | 51481-60-8 | 1g | $599 | 2024-03-01 | Buy |
| Sigma-Aldrich | N7758 | Naloxone hydrochloride dihydrate ≥98% (TLC and titration), powder | 51481-60-8 | 5g | $760 | 2024-03-01 | Buy |
| Sigma-Aldrich | N7758 | Naloxone hydrochloride dihydrate ≥98% (TLC and titration), powder | 51481-60-8 | 250mg | $185 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000695 | Naloxone for peak identification European Pharmacopoeia (EP) Reference Standard | 51481-60-8 | y0000695 | $220 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR1802 | Naloxone hydrochloride dihydrate Pharmaceutical Secondary Standard; Certified Reference Material | 51481-60-8 | 300mg | $267 | 2024-03-01 | Buy |
Naloxone hydrochloride dihydrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, hygroscopic, crystalline powder.
Uses
Antagonist (to narcotics).
Uses
Naloxone Hydrochloride Dihydrate is a specific opioid antagonist. Narcotic antagonist.
brand name
Narcan (Bristol-Myers Squibb); Narcan (Endo).
Biochem/physiol Actions
Competitive antagonist for μ, κ, δ, and σ opioid receptors; blocks the action of σ-agonists at opioid sites. Naloxone′s antagonistic effect last for about 45 min and thus, requires repeated dosage. It results in critical side effects such as pulmonary edema.
Purification Methods
This opiate antagonist has been recrystallised from EtOH/Et2O or H2O. It is soluble in H2O (5%) and EtOH but insoluble in Et2O. The free base has m 184o (177-178o also reported) after recrystallisation from EtOAc, and [] D -194.5o (c 0.93, CHCl3). [Olofson et al. Tetrahedron Lett 1567 1977, Gold et al. Med Res Rev 2 211 1982.]
Naloxone hydrochloride dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 109)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22783 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20286 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from Naloxone hydrochloride dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-27 | Naloxone hydrochloride dihydrate
51481-60-8
|
US $0.00-0.00 / g/Bag | 1g | 98%-102% | 1000G | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2019-07-06 | Naloxone hydrochloride dihydrate
51481-60-8
|
US $1.00 / kg | 1kg | 95%-98% | 100kg | Career Henan Chemical Co |
-
- Naloxone hydrochloride dihydrate
51481-60-8
- US $0.00-0.00 / g/Bag
- 98%-102%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Naloxone hydrochloride dihydrate
51481-60-8
- US $1.00 / kg
- 95%-98%
- Career Henan Chemical Co
51481-60-8(Naloxone hydrochloride dihydrate)Related Search:
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Naloxone hydrochloride dihydrate CRS
Naloxone for peak identification CRS
Naloxone hydrochloride dihydrate USP/EP/BP
Naloxone for peak identification (Y0000695)Q: What is
Naloxone for peak identification (Y0000695) Q: What is the CAS Number of
Naloxone for peak identification (Y0000695)
Naloxone hydrochloride dihydrateQ: What is
Naloxone hydrochloride dihydrate Q: What is the CAS Number of
Naloxone hydrochloride dihydrate Q: What is the storage condition of
Naloxone hydrochloride dihydrate Q: What are the applications of
Naloxone hydrochloride dihydrate
51481-60-8
C19H21NO4HCl2H2O
C19H26ClNO6
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