ChemicalBook >> CAS DataBase List >>5-Fluoroindole

5-Fluoroindole

CAS No.
399-52-0
Chemical Name:
5-Fluoroindole
Synonyms
5-FLUORO-1H-INDOLE;NSC 88613;5-FLUOROINDOLE;AKOS JY2082903;BUTTPARK 24\07-33;Indole, 5-fluoro-;5-Fluoroindole98%;5-Fluoroindole>5-Fluoroindole 98%;5-Fluoroindole,99%
CBNumber:
CB7445446
Molecular Formula:
C8H6FN
Molecular Weight:
135.14
MDL Number:
MFCD00005671
MOL File:
399-52-0.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

5-Fluoroindole Properties

Melting point 45-48 °C (lit.)
Boiling point 120 °C / 1mmHg
Density 1.1203 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 16.16±0.30(Predicted)
form Crystalline Powder
color Off-white
BRN 112350
CAS DataBase Reference 399-52-0(CAS DataBase Reference)
FDA UNII ZL8W3FGT5K
NIST Chemistry Reference 1H-indole, 5-fluoro-(399-52-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

5-Fluoroindole price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F9108 5-Fluoroindole 98% 399-52-0 1g $60.9 2024-03-01 Buy
TCI Chemical F0369 5-Fluoroindole >98.0%(GC) 399-52-0 1g $34 2024-03-01 Buy
TCI Chemical F0369 5-Fluoroindole >98.0%(GC) 399-52-0 5g $109 2024-03-01 Buy
Alfa Aesar A15346 5-Fluoroindole, 99% 399-52-0 1g $50.65 2024-03-01 Buy
Alfa Aesar A15346 5-Fluoroindole, 99% 399-52-0 5g $194.65 2024-03-01 Buy
Product number Packaging Price Buy
F9108 1g $60.9 Buy
F0369 1g $34 Buy
F0369 5g $109 Buy
A15346 1g $50.65 Buy
A15346 5g $194.65 Buy

5-Fluoroindole Chemical Properties,Uses,Production

Chemical Properties

off-white crystalline powder

Uses

  • Reactant for preparation of 5-HT6 receptor ligands
  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Reactant for preparation of antitumor agents
  • Reactant for preparation of antibacterial agents
  • Reactant for preparation of immunosuppressive agents
  • Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
  • Reactant for preparation of Myeloperoxidase Inhibitors
  • Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors

Uses

• ;Reactant for preparation of 5-HT6 receptor ligands1• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Reactant for preparation of antitumor agents3• ;Reactant for preparation of antibacterial agents4• ;Reactant for preparation of immunosuppressive agents5• ;Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes6• ;Reactant for preparation of Myeloperoxidase Inhibitors7• ;Reactant fo

Uses

5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.

Definition

ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole.

56341-41-4
399-52-0
Synthesis of 5-Fluoroindole from 5-Fluoro-2-oxindole
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View Lastest Price from 5-Fluoroindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Fluoroindole pictures 2022-02-22 5-Fluoroindole
399-52-0
US $0.00 / KG 1KG 97.1% 100 tons Honest Joy Holdings Limited
5-Fluoroindole  in stock  Factory  pictures 2020-06-02 5-Fluoroindole in stock Factory
399-52-0
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 largest production capacity Factory Chemwill Asia Co.,Ltd.
5-Fluoroindole  pictures 2020-02-26 5-Fluoroindole
399-52-0
US $0.00-0.00 / KG 10g 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
  • 5-Fluoroindole  pictures
  • 5-Fluoroindole
    399-52-0
  • US $0.00-0.00 / KG
  • 99.0%+
  • Shaanxi Dideu Medichem Co. Ltd
5-FLUORO-3-METHYLINDOLE 1H-Indole, 5-fluoro- 5-FLUOROINDOLE(5FI) 5- Fluoroindole,5-Fluoro-1H-indole 5-Fluoroindole, 98% 1GR NSC 88613 5-Fluoroindole 98% Indole, 5-fluoro- BUTTPARK 24\07-33 AKOS JY2082903 5-FLUOROINDOLE 5-Fluoroindole98% 5-Fluoroindole,99% 5-Fluoro-1H-indole 99% 5-Fluoro-1H-indole99% 5-FLUOROINDOLE TOSYLATE 5-Fluoroindole in stock Factory 5-Fluoroindole> 5-Fluoroindole ISO 9001:2015 REACH 5-FLUORO-1H-INDOLE 5-Fluoroindole in isooctane 399-52-0 14508-48-7 339-52-0 389-52-0 Building Blocks Simple Indoles Indoles Heterocyclic Building Blocks Indoles Indole Series Building Blocks Heterocyclic Building Blocks Simple Indoles Indole CHIRAL CHEMICALS Fluorinated heterocyclic series Heterocyclic Fluorinated Building Blocks Other Fluorinated Heterocycles Building Blocks C7 to C9 Chemical Synthesis Fluorinated Building Blocks Heterocyclic Building Blocks blocks FluoroCompounds IndolesOxindoles Indole/indoline/oxindole Indole and Indoline Indoles and derivatives