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AURINTRICARBOXYLIC ACID

AURINTRICARBOXYLIC ACID structure

CAS No.: 4431-00-9

Chemical Name:: AURINTRICARBOXYLIC ACID

Synonyms: ATA;SKL331;e)-6-oxo-;aluminonfreeacid;TIMTEC-BB SBB005410;AURINTRICARBONIC ACID;aurintricarboxylicaci;LABOTEST-BB LT00080677;AURINTRICARBOXYLIC ACID;aurinetricarboxylic acid

CBNumber:: CB7463004

Molecular Formula:: C22H14O9

Molecular Weight:: 422.34

MDL Number:: MFCD00011663

MOL File:: 4431-00-9.mol

MSDS File:: SDS

Last updated:2024-11-18 17:01:59

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AURINTRICARBOXYLIC ACID Properties

Melting point	300 °C(lit.)
Boiling point	458.99°C (rough estimate)
Density	1.3860 (rough estimate)
refractive index	1.6230 (estimate)
storage temp.	+15C to +30C
solubility	1 M NH₄OH: 10 mg/mL
form	powder
pka	2.20±0.20(Predicted)
color	dark red to brown
Water Solubility	Insoluble in water.
BRN	2228904
CAS DataBase Reference	4431-00-9(CAS DataBase Reference)
FDA UNII	NP9O8E29QW
EPA Substance Registry System	Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy- (4431-00-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

GU4790000

TSCA

Yes

NFPA 704

	0
2		0

AURINTRICARBOXYLIC ACID price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A1895	Aurintricarboxylic acid practical grade, ≥85% (titration), powder	4431-00-9	5g	$69.6	2024-03-01	Buy
Sigma-Aldrich	189400	Aurintricarboxylic Acid	4431-00-9	100mg	$56.2	2024-03-01	Buy
Alfa Aesar	A15905	Aurintricarboxylic acid	4431-00-9	5g	$47	2024-03-01	Buy
Alfa Aesar	A15905	Aurintricarboxylic acid	4431-00-9	25g	$128.65	2024-03-01	Buy
Sigma-Aldrich	A1895	Aurintricarboxylic acid practical grade, ≥85% (titration), powder	4431-00-9	25g	$240	2024-03-01	Buy

Product number	Packaging	Price	Buy
A1895	5g	$69.6	Buy
189400	100mg	$56.2	Buy
A15905	5g	$47	Buy
A15905	25g	$128.65	Buy
A1895	25g	$240	Buy

AURINTRICARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

deep red coarse crystalline powder

Uses

endonuclease inhibitor; apoptosis inhibitor, topoisomerase II inhibitor

Uses

Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.

Definition

ChEBI: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.

Purification Methods

The acid is dissolved in aqueous NaOH, NaHSO3 solution is added until the colour is discharged and then the tricarboxylic acid is precipitated with HCl. [Heisig & Lauer Org Synth Coll Vol I 54 1941, Beilstein 10 IV 4161]. Do not extract the acid with hot water because it softens, forming a viscous mass. Make a solution in aqueous NH3. Aluminon is the NH4 salt.

AURINTRICARBOXYLIC ACID synthesis

Synthesis of AURINTRICARBOXYLIC ACID from Formaldehyde and Salicylic acid

AURINTRICARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

4-Nitrobenzoyl chloride Methylenedisalicylic acid 5,5'-Methylenedisalicylic acid NITROUS ACID Sulfuric acid

Methanol Formaldehyde Salicylic acid

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Preparation Products

AURINTRICARBOXYLIC ACID Suppliers

Global( 127)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38632	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49978	58

Supplier	Advantage
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
TargetMol Chemicals Inc.	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from AURINTRICARBOXYLIC ACID manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-18	Aurintricarboxylic acid 4431-00-9	US $30.00-61.00 / mg		95%	10g	TargetMol Chemicals Inc.
2019-07-06	AURINTRICARBOXYLIC ACID 4431-00-9	US $1.00 / kg	1kg	95%-99%	100kg	Career Henan Chemical Co
2019-07-06	AURINTRICARBOXYLIC ACID 4431-00-9	US $1.00 / kg	1kg	95%-99%	100kg	Career Henan Chemical Co

Aurintricarboxylic acid
4431-00-9
US $30.00-61.00 / mg
95%
TargetMol Chemicals Inc.

AURINTRICARBOXYLIC ACID
4431-00-9
US $1.00 / kg
95%-99%
Career Henan Chemical Co

AURINTRICARBOXYLIC ACID
4431-00-9
US $1.00 / kg
95%-99%
Career Henan Chemical Co

AURINTRICARBOXYLIC ACID Spectrum

AURINTRICARBOXYLIC ACID(4431-00-9)IR1 AURINTRICARBOXYLIC ACID(4431-00-9)IR2

4431-00-9(AURINTRICARBOXYLIC ACID)Related Search:

Sorbic acid Aluminon 3-VINYLBENZALDEHYDE 5-PHENYLPENTA-2,4-DIENOIC ACID 5-Methylsalicylaldehyde

TRANS-2-PENTENOIC ACID TRANS-2-PENTEN-1-OL 5-Methylsalicylic acid 5,5'-Methylenedisalicylic acid 2,4-DIMETHYL-1,3-PENTADIENE

1-METHYL-1,4-CYCLOHEXADIENE (E,E)-2,4-Hexadienal TRANS,TRANS-2,4-HEXADIEN-1-OL trans-2-Methyl-2-pentenoic acid m,alpha-dimethylstyrene

AURINTRICARBOXYLIC ACID ROSOLIC ACID Allylacetic acid

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TIMTEC-BB SBB005410 LABOTEST-BB LT00080677 ATA 5,5-(3-carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid) aurinetricarboxylic acid AURINTRICARBOXYLIC ACID FREE ACIDPRACTIC AL GRADE Aurintricarboxylic Acid (Ata) AURINTRICARBONIC ACID Aurintricarboxylic acid, tech., 85% 1-Oxo-4-[bis(3-carboxy-4-hydroxyphenyl)methylene]-2,5-cyclohexadiene-2-carboxylic acid 5,5'-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(2-hydroxybenzoic acid) Aurintricarboxylic acid,85%,tech. 5,5'-((3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)Methylene)bis(2-hydroxybenzoic acid) AURINTRICARBOXYLIC ACID 1,4-cyclohexadiene-1-carboxylicacid,3-(bis(3-carboxy-4-hydroxyphenyl)methylen 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-benzoicaci aluminonfreeacid e)-6-oxo- 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene) bis(2-hydroxybenzoic acid) Benzoic acid, 3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy- aurintricarboxylicaci Aurintricarboxylic Acids (Technical Grade) SKL331 5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem ATA(Aurintricarboxylic acid) 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene)bis(2-hydroxybenzoic acid) 4431-00-9 C22H14O9 DNA metabolism DNA Repair Regulators BioChemical Cell Signaling and Neuroscience Cell Biology Apoptosis and Cell Cycle Colours, Dyes, Indicators & Pigments