Phenyl chlorothionocarbonate
- CAS No.
- 1005-56-7
- Chemical Name:
- Phenyl chlorothionocarbonate
- Synonyms
- O-Phenyl carbonochloridothioate;PHENYL CHLOROTHIONOFORMATE;O-PHENYL CHLOROTHIONOFORMATE;PHENYL THIONOCHLOROFORMATE;phenylcarbonochloridothioate;phenyl thioxochloroformate;Phenoxythiocarbonyl chloride;O-phenyl chloromethanethioate;NSC 99103;Phenoxythiocar
- CBNumber:
- CB7480281
- Molecular Formula:
- C7H5ClOS
- Molecular Weight:
- 172.63
- MDL Number:
- MFCD00004920
- MOL File:
- 1005-56-7.mol
- MSDS File:
- SDS
Melting point | 51 °C |
---|---|
Boiling point | 81-83 °C/6 mmHg (lit.) |
Density | 1.248 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 179 °F |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform, Ethyl Acetate |
form | Liquid |
Specific Gravity | 1.248 |
color | Clear yellow |
Water Solubility | decomposes |
Sensitive | Moisture Sensitive |
BRN | 774830 |
CAS DataBase Reference | 1005-56-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
Hazard Codes | C | |||||||||
Risk Statements | 34 | |||||||||
Safety Statements | 26-36/37/39-45 | |||||||||
RIDADR | UN 3265 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29309070 | |||||||||
NFPA 704 |
|
Phenyl chlorothionocarbonate price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 234524 | O-Phenyl chlorothionoformate 99% | 1005-56-7 | 5g | $96.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 234524 | O-Phenyl chlorothionoformate 99% | 1005-56-7 | 1g | $28.2 | 2023-06-20 | Buy |
TCI Chemical | P1236 | Phenyl Chlorothionoformate >98.0%(GC)(T) | 1005-56-7 | 5g | $32 | 2024-03-01 | Buy |
TCI Chemical | P1236 | Phenyl Chlorothionoformate >98.0%(GC)(T) | 1005-56-7 | 25g | $97 | 2024-03-01 | Buy |
Alfa Aesar | L00838 | Phenyl chlorothionoformate, 98+% | 1005-56-7 | 1g | $28.65 | 2024-03-01 | Buy |
Phenyl chlorothionocarbonate Chemical Properties,Uses,Production
Chemical Properties
CLEAR YELLOW LIQUID
Uses
O-Phenyl chlorothionoformate has been used in:
- stereodirected synthesis of optically active, (?)-mintlactone
- synthesis of peptide α-thioesters having a variety of C-terminal amino acids
- synthesis of scyllo-inositol derivatives
- thionocarbonylation of unprotected thymine nucleosides
- preparation of phenoxythiocarbonyl esters of protected ribonucleosides
Uses
Phenyl Chlorothionoformate is used in the preparation of an bicyclic thymidine analogs as selective inhibitors of Thymidine monophosphate kinase Mycobacterium tuberculosis (TMPKmt).
Purification Methods
Purify it by dissolving in CHCl3, washing with H2O, drying (CaCl2), filtering, evaporating and distilling twice under a vacuum to give a clear yellow liquid. It is reactive and POISONOUS—work in a fume cupboard. Store it in sealed ampoules under N2. A possible impurity is O,O'-diphenyl thiocarbonate which has m 106o and remains behind in the distilling flask. [B.gemann et al. in Methoden Der Organischen Chemie (Houben-Weyl) 4th edn (E. Müller Ed.) Vol 9 Schwefel-Selen-Tellur Verbindungen pp. 807-808 1955, Rivier & Schalch Helv Chim Acta 6 612 1923, Kalson Chem Ber 20, 2384 1987, Rivier & Richard Helv Chim Acta 8 490 1925, Sch.nberg & Varga Justus Liebigs Ann Chem 483 176 1930, Sch.nberg & Vargha Chem Ber 64 1390 1931, Beilstein 6 III 609.]
Phenyl chlorothionocarbonate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 1418 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21673 | 55 |
Nanjing MSN chemical Co., Ltd | 25-57015632 +8618913029712 | export@msnchem.com | China | 25 | 34 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29897 | 58 |
Wuhan Chemwonders Technology Inc. | 027-85778276 | info@chemwonders.com | CHINA | 176 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Phenyl chlorothionocarbonate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-07-16 | Phenyl chlorothionocarbonate
1005-56-7
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | ||
2019-07-06 | Phenyl chlorothionocarbonate
1005-56-7
|
US $1.00 / kg | 1kg | 95%-99% | as request | Career Henan Chemical Co |
- Phenyl chlorothionocarbonate
1005-56-7
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
- Phenyl chlorothionocarbonate
1005-56-7
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co