ChemicalBook >> CAS DataBase List >>CAERULOMYCIN A

CAERULOMYCIN A

CAS No.
21802-37-9
Chemical Name:
CAERULOMYCIN A
Synonyms
CERULOMYCIN;CAERULOMYCIN;AERULOMYCIN A;Carulomycin A;CAERULOMYCIN A;Caerulomycin, Cerulomycin;CeruloMycin, CaeruloMycin A;Fungal,Antibiotic,Caerulomycin A,inhibit,Inhibitor;4-Methoxy-2,2'-bipyridine-6-carbaldehyde (E)-oxime;(E)-4-Methoxy-[2,2'-bipyridine]-6-carbaldehyde oxime
CBNumber:
CB7484496
Molecular Formula:
C12H11N3O2
Molecular Weight:
229.23
MDL Number:
MFCD03093715
MOL File:
21802-37-9.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

CAERULOMYCIN A Properties

Melting point 173 °C
Boiling point 420.0±45.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up to 10 mg/ml).
form solid
pka 9.89±0.50(Predicted)
color White
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HS Code  2933399990
NFPA 704
0
2 0

CAERULOMYCIN A price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C6374 Caerulomycin A from 21802-37-9 1mg $449 2024-03-01 Buy
Cayman Chemical 27625 Caerulomycin A 21802-37-9 1mg $340 2024-03-01 Buy
Cayman Chemical 27625 Caerulomycin A 21802-37-9 5mg $1186 2024-03-01 Buy
TRC C700030 Caerulomycin A 21802-37-9 1mg $395 2021-12-16 Buy
Biorbyt Ltd orb546133 Caerulomycin A >98% 21802-37-9 100μg $209.1 2021-12-16 Buy
Product number Packaging Price Buy
C6374 1mg $449 Buy
27625 1mg $340 Buy
27625 5mg $1186 Buy
C700030 1mg $395 Buy
orb546133 100μg $209.1 Buy

CAERULOMYCIN A Chemical Properties,Uses,Production

Description

Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion?in vitro?and?in vivo.1 Caerulomycin A induces expansion of regulatory T cells by via interfering with IFNγ -induced STAT1 signaling.2

Uses

Caerulomycin A is a pyridine derived antiobiotic with a broad spectrum of bioactivity.

Uses

Caerulomycin is a rare and unusual antibiotic containing a core 2, 2’-bispyridyl with an oxime substituent, produced by a strain of Streptomyces caeruleus isolated in Canada in 1959. Caerulomycin is active against fungi and some protozoans, and is weakly active against bacteria. While its discovery has stimulated some synthetic effort, little is known about the mode and spectrum of action of caerulomycin.

Definition

ChEBI: Caerulomycin A is a pyridine alkaloid that is 2,2'-bipyridine substituted by a methoxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity. It has a role as an antineoplastic agent, a marine metabolite and a bacterial metabolite. It is an aldoxime, an aromatic ether, a member of bipyridines and a pyridine alkaloid. It derives from a hydride of a 2,2'-bipyridine.

References

1) Singla?et al. (2014),?Caerulomycin A suppresses immunity by inhibiting T cell activity; PLoS One,?9(10)?e107051 2) Gurram?et al. (2014),?Caerulomycin A enhances transforming growth factor-beta (TGF-β)-Smad3 protein signaling by suppressing interferon-gamma (IFN-γ)-signaling to expand regulatory T cells (Tregs); J. Biol. Chem.?289?17515

CAERULOMYCIN A Preparation Products And Raw materials

Raw materials

Preparation Products

CAERULOMYCIN A Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38632 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33338 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+86-18791163155 +86-13119157289 13119157289@163.com China 2973 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55

View Lastest Price from CAERULOMYCIN A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Caerulomycin A pictures 2024-11-19 Caerulomycin A
21802-37-9
US $247.00-795.00 / mg 97.51% 10g TargetMol Chemicals Inc.
Caerulomycin A pictures 2024-11-19 Caerulomycin A
21802-37-9
US $247.00-795.00 / mg 97.51% 10g TargetMol Chemicals Inc.
AERULOMYCIN A pictures 2019-12-26 AERULOMYCIN A
21802-37-9
US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co
  • Caerulomycin A pictures
  • Caerulomycin A
    21802-37-9
  • US $247.00-795.00 / mg
  • 97.51%
  • TargetMol Chemicals Inc.
  • Caerulomycin A pictures
  • Caerulomycin A
    21802-37-9
  • US $247.00-795.00 / mg
  • 97.51%
  • TargetMol Chemicals Inc.
  • AERULOMYCIN A pictures
  • AERULOMYCIN A
    21802-37-9
  • US $1.00 / g
  • ≥98%
  • Career Henan Chemical Co
(E)-4-Methoxy-[2,2'-bipyridine]-6-carbaldehyde oxime 4-Methoxy-2,2'-bipyridine-6-carbaldehyde (E)-oxime (2,2'-Bipyridine)-6-carboxaldehyde, 4-methoxy-, oxime, (E)- CeruloMycin, CaeruloMycin A CAERULOMYCIN CAERULOMYCIN A Carulomycin A CERULOMYCIN Caerulomycin, Cerulomycin AERULOMYCIN A Fungal,Antibiotic,Caerulomycin A,inhibit,Inhibitor (E)-4-Methoxy-[2,2'-bipyridine]-6-carbaldehyde oxime 21802-37-9 C12H11N3O2 Antibiotic