VIOMYCIN SULFATE
- CAS No.
- 37883-00-4
- Chemical Name:
- VIOMYCIN SULFATE
- Synonyms
- viocinsulfate;viomycin-sulfat;VIOMYCIN SULFATE;viomycin sulphate;florimycinsulfate;solfatodiviomicina;celicomycin-sulfate;viomycin,sulfate(salt);Viomycin Sulfate (1715000);Tuberactinomycin B sulfate salt
- CBNumber:
- CB7497829
- Molecular Formula:
- C25H45N13O14S
- Molecular Weight:
- 783.77
- MDL Number:
- MFCD31810484
- MOL File:
- 37883-00-4.mol
| Melting point | 266° (dec) |
|---|---|
| alpha | D18 -29.5° (c = 1 in H2O) |
| storage temp. | 2-8°C |
| FDA UNII | LKO141R05V |
SAFETY
Risk and Safety Statements
| Hazard Codes | T |
|---|---|
| Risk Statements | 61-20/21/22 |
| Safety Statements | 53-22-36/37-45 |
| RIDADR | 3249 |
| RTECS | ZA3960000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 in mice (mg/kg): 240 i.v. (Finlay); 1750 s.c. (Keller) |
VIOMYCIN SULFATE Chemical Properties,Uses,Production
Originator
Vinactane,Ciba,US ,1953
Manufacturing Process
Viomycin is produced by inoculating a nutrient medium with a viable strain of the organism Actinomyces vinaceus. A method for the production of viomycin is set forth in US Patent 2,663,445 comprising inoculating a medium containing soy peptone, beef extract, dextrose, sodium chloride and a silicone antifoaming agent with a spore suspension of Actinomyces vinaceus and incubating the inoculated medium for 120 hours at a temperature of 26°C while passing sterile air through the medium at a rate of 500 ml per liter of medium per minute.
brand name
Viocin Sulfate (Pfizer).
Therapeutic Function
Antitubercular
Purification Methods
Viocin crystallises from H2O/EtOH and is dried in a vacuum. The dry material is hygroscopic and should be stored dry. The UV has max at 268 and 285nm (log 4.4 and 4.2) in H2O. [Kitigawa et al. Chem Pharm Bull Jpn 20 2176 1972.] The hydrochloride forms hygroscopic plates with m 270o(dec), []18 -16.6o (c 1, H2O) with max at 268nm (log 4.5) in H2O; 268nm (log 4.4) in 0.1N HCl and at 285nm (log 4.3) in 0.1N NaOH. [Beilstein 26 III/IV 4245.]
VIOMYCIN SULFATE Preparation Products And Raw materials
Raw materials
Preparation Products
VIOMYCIN SULFATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Supplier | Advantage |
|---|---|
| Sinopharm Chemical Reagent Co,Ltd. | 79 |
| BOC Sciences | 65 |