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AMINOGUANIDINE HYDROCHLORIDE

CAS No.
1937-19-5
Chemical Name:
AMINOGUANIDINE HYDROCHLORIDE
Synonyms
2-aminoguanidine hydrochloride;Aminoguanidine HCL;GUANYLHYDRAZINEHCL;AMINOGUANIDINE SALT;Aminoguanidine salts;CP-12009-18 tartrate;amino-guanidinhydrochloride;Aminoguanidine hydrochoride;Aminoguanadine hydrochloride;AMINOGUANIDINE HYDROCHLORIDE
CBNumber:
CB7497900
Molecular Formula:
CH7ClN4
Molecular Weight:
110.54608
MDL Number:
MFCD00039074
MOL File:
1937-19-5.mol
MSDS File:
SDS
Last updated:2024-11-19 20:33:22

AMINOGUANIDINE HYDROCHLORIDE Properties

Melting point 162-166 °C(lit.)
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Completely soluble in water
form Crystals
color White to off-white
Water Solubility 506.7g/L at 20℃
Merck 13,440
BRN 3909606
LogP -3.55 at 20℃
CAS DataBase Reference 1937-19-5(CAS DataBase Reference)
FDA UNII A2Z7G2RGAH
EPA Substance Registry System Hydrazinecarboximidamide, monohydrochloride (1937-19-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H317-H411
Precautionary statements  P261-P272-P273-P280-P302+P352-P333+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  ME8430000
10-21
HS Code  29280000
NFPA 704
0
1 0

AMINOGUANIDINE HYDROCHLORIDE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 396494 Aminoguanidine hydrochloride ≥98% 1937-19-5 25g $70.3 2024-03-01 Buy
Sigma-Aldrich 396494 Aminoguanidine hydrochloride ≥98% 1937-19-5 100g $214 2024-03-01 Buy
TCI Chemical A1129 Aminoguanidine Hydrochloride >98.0%(T) 1937-19-5 25g $52 2024-03-01 Buy
TCI Chemical A1129 Aminoguanidine Hydrochloride >98.0%(T) 1937-19-5 100g $113 2024-03-01 Buy
Cayman Chemical 81530 Aminoguanidine (hydrochloride) ≥98% 1937-19-5 10g $25 2024-03-01 Buy
Product number Packaging Price Buy
396494 25g $70.3 Buy
396494 100g $214 Buy
A1129 25g $52 Buy
A1129 100g $113 Buy
81530 10g $25 Buy

AMINOGUANIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Aminoguanidine Hydrochloride is used in the synthetic preparation of highly selective and potent G-protein-coupled receptor kinase 2 (GRK2) inhibitor for potential treatment of heart failure.

Description

Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 μM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.

Chemical Properties

white to off-white crystals

Uses

antitussive

Uses

Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.

Uses

a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin

General Description

Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Inhibits both constitutive and inducible nitric oxide synthetase.

Global( 273)Suppliers
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Jiaxing Dongliang Pharmaceutical Technology Co.,Ltd.
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View Lastest Price from AMINOGUANIDINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aminoguanidine Hydrochloride pictures 2024-11-29 Aminoguanidine Hydrochloride
1937-19-5
US $85.00-25.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
Aminoguanidine hydrochloride pictures 2024-11-19 Aminoguanidine hydrochloride
1937-19-5
US $36.00-75.00 / mg 100% 10g TargetMol Chemicals Inc.
Aminoguanidine hydrochloride pictures 2024-11-19 Aminoguanidine hydrochloride
1937-19-5
US $36.00-75.00 / mg 100% 10g TargetMol Chemicals Inc.
amino-guanidinhydrochloride hydrazinecarboximidamidehydrochloride carbazamidine monohydrochloride AMINOGUANIDINE HYDROCHLORIDE, 98+% AMINOGUANIDINE SALT GUANYLHYDRAZINEHCL GUANIDINE,AMINO-,MONOHYDROCHLORIDE Aminoguanidine hydrochoride 1-Aminoguanidine·hydrochloride Aminoguanidine salts D015 AMinoguanidine hydrochloride AMinoguanidine hydrochloride, 98% 25GR AMinoguanidine Hydrochloride, 98.0%(T) Aminoguanidine monohydrochloride Hydrazinecarboximidamide hydrochlorideHydrochloride Aminoguanadine hydrochloride 98% Metformin Impurity 15(Aminoguanidine hydrochloride) Aminoguanadine hydrochloride Aminoguanidine hydrochloride, 98%, a diamine oxidase and NO synthase inhibitor AminoguanidineHydrochloride> CP-12009-18 tartrate AMINOGUANIDINE HYDROCHLORIDE ISO 9001:2015 REACH Aminoguanidine Hydrochloride (AGH) TIANFU-CHEM - AMINOGUANIDINE HYDROCHLORIDE Aminoguanidine HCL 2-aminoguanidine hydrochloride Aminoguanidine Hydrochloride CAS NO.1937-19-5 AMINOGUANIDINE HYDROCHLORIDE Ethyl 2-phenylacetoacetate 5413-05-8 Nitric oxide synthases,GER 11,GER-11,NOS,Aminoguanidine hydrochloride,Aminoguanidinium,NO Synthase,inhibit,GER11,Inhibitor,Aminoguanidine 1937-19-5 1973-19-5 NH2NHCNHNH2HCl CH7ClN4 CH6N4HClH2NNHCNHNH2HCl CH6N4ClH Signalling TUSACAPINE Nitric Oxide Pharmaceutical Intermediates