Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>RAC 8-HYDROXY EFAVIRENZ

RAC 8-HYDROXY EFAVIRENZ

RAC 8-HYDROXY EFAVIRENZ Structure
RAC 8-HYDROXY EFAVIRENZ structure
CAS No.
205754-33-2
Chemical Name:
RAC 8-HYDROXY EFAVIRENZ
Synonyms
8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;(S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
CBNumber:
CB7501021
Molecular Formula:
C14H9ClF3NO3
Molecular Weight:
331.67
MDL Number:
MFCD09840726
MOL File:
205754-33-2.mol
MSDS File:
SDS
Last updated:2024-10-23 20:41:25
Request For Quotation

RAC 8-HYDROXY EFAVIRENZ Properties

Melting point 144-154°C
Boiling point 373.6±42.0 °C(Predicted)
Density 1?+-.0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Acetonitrile: soluble; DMSO: soluble; Methanol: soluble
form A solid
pka 7.18±0.40(Predicted)
color White to off-white
FDA UNII P8S49CKH6L

RAC 8-HYDROXY EFAVIRENZ price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27853 8-hydroxy Efavirenz 205754-33-2 1mg $605 2024-03-01 Buy
Usbiological H9044-30 rac 8-Hydroxy Efavirenz 205754-33-2 1mg $460 2021-12-16 Buy
TRC H941830 8-HydroxyEfavirenz(~90%) 205754-33-2 2.5mg $6595 2021-12-16 Buy
Medical Isotopes, Inc. 51706 8-HydroxyEfavirenz 205754-33-2 50mg $7500 2021-12-16 Buy
American Custom Chemicals Corporation API0010043 8-HYDROXYEFAVIRENZ 95.00% 205754-33-2 5MG $504.72 2021-12-16 Buy
Product number Packaging Price Buy
27853 1mg $605 Buy
H9044-30 1mg $460 Buy
H941830 2.5mg $6595 Buy
51706 50mg $7500 Buy
API0010043 5MG $504.72 Buy

RAC 8-HYDROXY EFAVIRENZ Chemical Properties,Uses,Production

Description

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemical Properties

Off-White Solid

Uses

8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor.

Uses

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

RAC 8-HYDROXY EFAVIRENZ Preparation Products And Raw materials

Raw materials

Preparation Products

RAC 8-HYDROXY EFAVIRENZ Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 Sales@pipitech.com China 3633 55
Shanghai Devinchem Ltd 027-65318838 13646286950 sales@devinchem.com China 2997 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94657 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 lucy@atkchemical.com China 9952 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
TargetMol Chemicals Inc. 		58
Guangzhou PI PI Biotech Inc 55
Shanghai Devinchem Ltd 58
J & K SCIENTIFIC LTD. 76
Chemsky (shanghai) International Co.,Ltd 60
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
Shanghai Hongye Biotechnology Co. Ltd 58

View Lastest Price from RAC 8-HYDROXY EFAVIRENZ manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-hydroxy Efavirenz pictures 2024-10-24 8-hydroxy Efavirenz
205754-33-2
 US $1510.00 / mg 10g TargetMol Chemicals Inc.

205754-33-2(RAC 8-HYDROXY EFAVIRENZ)Related Search:

SE 563 Efavirenz AMino Alcohol Ethyl CarbaMate rac Methyl Efavirenz Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) rac 8-Hydroxy Efavirenz
Efavirenz Related Compound C (20 mg) (6-chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline) 6-chloro-4-pent-1-ynyl-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one L 741211 Efavirenz rac 8,14-Dihydroxy Efavirenz
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine (Mixture of 2 Diastereomers) Efavirenz IP Impurity A rac 7-Hydroxy Efavirenz [4-Chloro-2-[(1S)-3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl)phenyl]carbamic Acid Methyl Ester
(S)-5-chloro-a-(Cyclopropylacetenyl)-2-[((4-methoxyphenyl)methyl)amino]-a- (trifluoromethyl) benzenemethanol (E-4) Enantiomer Efavirenz Efavirenz Impurity 13(7-Hydroxy Efavirenz)

1of4

RAC 8-HYDROXY EFAVIRENZ 8-HydroxyEfavirenz 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one Efavirenz Impurity 11(8-Hydroxy Efavirenz) 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)- 8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz 2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)- (S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one 205754-33-2 Metabolites Non-nucleoside Reverse Transcriptase Pharmaceuticals Intermediates & Fine Chemicals Isotope Labeled Compounds