ChemicalBook >> CAS DataBase List >>CDK4/6-IN-2
CDK4/6-IN-2
- CAS No.
- 1800506-48-2
- Chemical Name:
- CDK4/6-IN-2
- Synonyms
- AM24679P4;CDK4/6-IN-2;CDK4/6 inhibitor 2;Cyclin dependent kinase,CDK-4/6-IN-2,CDK,CDK4/6 IN 2,CDK4/6IN2,inhibit,Inhibitor;5-((4-ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine;2-Pyrimidinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-N-[5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyridinyl]-
- CBNumber:
- CB75419703
- Molecular Formula:
- C27H32F2N8
- Molecular Weight:
- 506.59
- MDL Number:
- MFCD32067908
- MOL File:
- 1800506-48-2.mol
Last updated:2024-07-02 08:55:17
CDK4/6-IN-2 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0083151 | CDK4/6-IN-2 99.82% | 1800506-48-2 | 5mg | $350 | 2021-12-16 | Buy |
ChemScene | CS-0083151 | CDK4/6-IN-2 99.82% | 1800506-48-2 | 10mg | $550 | 2021-12-16 | Buy |
ChemScene | CS-0083151 | CDK4/6-IN-2 99.82% | 1800506-48-2 | 50mg | $1650 | 2021-12-16 | Buy |
ChemScene | CS-0083151 | CDK4/6-IN-2 99.82% | 1800506-48-2 | 100mg | $2650 | 2021-12-16 | Buy |
CDK4/6-IN-2 Chemical Properties,Uses,Production
Description
CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1]. CDK4|2.7 nM (IC50)|CDK6|16 nM (IC50)
CDK4/6-IN-2 inhibits H358, H441, PC3, MV-4-11, JeKo-1, SW780, and HGC-27 cells with IC50s of 290.9, 147.8, 260.5, 139, 36.98, 162.5, and 316.4 nM, respectively[1].
References
[1]. Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.
CDK4/6-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
CDK4/6-IN-2 Suppliers
Global( 14)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Kaixin Chemical (Hong Kong) Limited | 010-88886666-01 13112345678 | loyson@tcypharm.com | China | 595 | 55 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10000 | 58 |
Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62163 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4738 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
CDK4/6-IN-2
CDK4/6 inhibitor 2
5-((4-ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine
AM24679P4
Cyclin dependent kinase,CDK-4/6-IN-2,CDK,CDK4/6 IN 2,CDK4/6IN2,inhibit,Inhibitor
2-Pyrimidinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-N-[5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyridinyl]-
1800506-48-2
CHFN