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Ilorasertib hydrochloride

CAS No.
1847485-91-9
Chemical Name:
Ilorasertib hydrochloride
Synonyms
ABT-348 hydrochloride;Ilorasertib hydrochloride;ILORASERTIB HYDROCHLORIDE (ABT-348 HYDROCHLORIDE)
CBNumber:
CB75540379
Molecular Formula:
C25H22ClFN6O2S
Molecular Weight:
525
MDL Number:
MFCD32201158
MOL File:
1847485-91-9.mol
Last updated:2024-07-02 08:55:17

Ilorasertib hydrochloride Properties

storage temp. Store at -20°C
solubility DMSO: 41.67 mg/mL (79.37 mM)
form Solid
color White to off-white

Ilorasertib hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0100459 Ilorasertib(hydrochloride) 98.91% 1847485-91-9 1mg $70 2021-12-16 Buy
ChemScene CS-0100459 Ilorasertib(hydrochloride) 98.91% 1847485-91-9 5mg $110 2021-12-16 Buy
ChemScene CS-0100459 Ilorasertib(hydrochloride) 98.91% 1847485-91-9 10mg $150 2021-12-16 Buy
ChemScene CS-0100459 Ilorasertib(hydrochloride) 98.91% 1847485-91-9 50mg $600 2021-12-16 Buy
ChemScene CS-0100459 Ilorasertib(hydrochloride) 98.91% 1847485-91-9 100mg $1100 2021-12-16 Buy
Product number Packaging Price Buy
CS-0100459 1mg $70 Buy
CS-0100459 5mg $110 Buy
CS-0100459 10mg $150 Buy
CS-0100459 50mg $600 Buy
CS-0100459 100mg $1100 Buy

Ilorasertib hydrochloride Chemical Properties,Uses,Production

Description

Ilorasertib hydrochloride (ABT-348 hydrochloride) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. Ilorasertib hydrochloride (ABT-348 hydrochloride) also suppresses RET tyrosine kinase, PDGFRβ and Flt1 with IC50s of 7 nM, 3 nM and 32 nM, respectively[1].

References

[1]. Glaser KB, et al. Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptor/platelet-derived growth factor receptor, and Src kinase families. J Pharmacol Exp Ther. 2012 Dec;343(3):617-27.

Ilorasertib hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Ilorasertib hydrochloride Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24648 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29802 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
ILORASERTIB HYDROCHLORIDE (ABT-348 HYDROCHLORIDE) Ilorasertib hydrochloride ABT-348 hydrochloride 1847485-91-9