ChemicalBook >> CAS DataBase List >>4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-
- CAS No.
- 3542-63-0
- Chemical Name:
- 4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-
- Synonyms
- CDK9-IN-10;CDK9IN10,CDK9 IN 10,CDK-9-IN-10;4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-
- CBNumber:
- CB75563578
- Molecular Formula:
- C22H16O5
- Molecular Weight:
- 360.36
- MDL Number:
- MFCD34469988
- MOL File:
- 3542-63-0.mol
- MSDS File:
- SDS
Last updated:2025-04-18 09:52:46
| Melting point | 220-221 °C(Solv: ethyl acetate (141-78-6); benzene (71-43-2)) |
|---|---|
| Boiling point | 621.1±55.0 °C(Predicted) |
| Density | 1.381±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, away from moisture and light |
| solubility | DMSO : ≥ 100 mg/mL (277.50 mM) |
| pka | 7.06±0.40(Predicted) |
| form | Solid |
| color | Yellow to brown |
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- Chemical Properties,Uses,Production
Uses
CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1].
IC 50
CDK9
References
[1] Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381. DOI:10.1016/j.bioorg.2018.08.028
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- Preparation Products And Raw materials
Raw materials
Preparation Products
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- Suppliers
Global( 12)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10523 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24739 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 48813 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-
CDK9-IN-10
CDK9IN10,CDK9 IN 10,CDK-9-IN-10
3542-63-0