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2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE structure

CAS No.: 511-13-7

Chemical Name:: 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE

Synonyms: ulo;sk74;ulone;sl501;detigon;coldrin;refugal;bayer-186;bayerb-186;pectolitan

CBNumber:: CB7744592

Molecular Formula:: C17H21Cl2NO

Molecular Weight:: 326.26

MDL Number:: MFCD00079013

MOL File:: 511-13-7.mol

MSDS File:: SDS

Last updated:2024-10-23 13:36:13

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2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Properties

Melting point	190-191°
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
CAS DataBase Reference	511-13-7(CAS DataBase Reference)
FDA UNII	69QQ58998Y

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS09
Signal word	Warning
Hazard statements	H410-H302
Precautionary statements	P264-P270-P301+P312-P330-P501-P273-P391-P501
Hazard Codes	T
Risk Statements	25
Safety Statements	36/37/39-45
RIDADR	3249
RTECS	DC7600000
HazardClass	6.1(b)
PackingGroup	III
Toxicity	LD50 orally in rats: 350 mg/kg; s.c. in mice: 95 mg/kg (Lorenz)

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	006963	Clofedanol Hydrochloride	511-13-7	50mg	$460	2021-12-16	Buy
TRC	C586920	ClofedanolHydrochloride	511-13-7	2.5g	$965	2021-12-16	Buy
Biosynth Carbosynth	FC20497	Clofedanol hydrochloride	511-13-7	25mg	$1000	2021-12-16	Buy
Biosynth Carbosynth	FC20497	Clofedanol hydrochloride	511-13-7	50mg	$1600	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0106065	2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 95.00%	511-13-7	500MG	$1963.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
006963	50mg	$460	Buy
C586920	2.5g	$965	Buy
FC20497	25mg	$1000	Buy
FC20497	50mg	$1600	Buy
HCH0106065	500MG	$1963.5	Buy

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Chemical Properties,Uses,Production

Originator

Abehol,Pliva

Uses

A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.

Definition

ChEBI: Chlophedianol hydrochloride is a diarylmethane.

Manufacturing Process

To a suspension of 330.0 g of sodamide (moistened with toluene) in 1500 ml of absolute ether, a solution of 1080.0 g of o-chlorobenzophenone and 350.0 g of acetonitrile in 3500 ml of absolute ether was gradually added dropwise, with stirring, such that the reaction temperature adjusted itself to 28°-30°C. The reaction mixture was stirred for 12 to 15 h at room temperature and was then added carefully to some ice water. The resulting solution was extracted 3 times with ether. The ether solution was washed with water, dried over Na2SO4, filtered, and finally concentrated. When 1 L of petroleum ether was added, 1240.0 g (96% of theoretical) of β-phenyl-β-o-chlorophenylhydroacrylonitrile (melting point 90°-92°C) precipitated.
500.0 g of the β-phenyl-β-o-chlorophenyl-hydroacrylonitrile were dissolved in 3 L of methanol and hydrogenated in the presence of 50.0 g of Raney cobalt at a temperature of 60°-70°C and a pressure of 80-85 ATM. Two moles of hydrogen were absorbed, and after separation of the methanolic solution from the catalyst, 450.0 g of 1-o-chlorophenyl-1-phenyl-3-aminopropanol-1 of melting point 117°C were obtained.
Catalytic methylation of 1-o-chlorophenyl-1-phenyl-3-aminopropanol-1 (hydrogenation in the presence of 2.2 mol of formaldehyde in aqueous methanol with Raney nickel catalyst) yielded 450.0 g of l-o-chlorophenyl-1- phenyl-3 dimethylaminopropanol-1 of melting point 120°C.
In practice it is usually used as hydrochloride.

brand name

Ulo (3M Pharmaceuticals).

Therapeutic Function

Antitussive

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

(2-Chlorophenyl)phenyl-methanone

Preparation Products

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	1022@dideu.com	China	3882	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21632	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29871	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49476	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15352	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9720	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
TopScience Biochemical	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
AFINE CHEMICALS LIMITED	58
changzhou huayang technology co., ltd	58

View Lastest Price from 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-10-24	Chlophedianol Hydrochloride 511-13-7	US $1980.00-1520.00 / mg			10g	TargetMol Chemicals Inc.
2024-07-15	2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 511-13-7	US $0.10 / KG	1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd
2019-07-12	2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 511-13-7	US $1.00 / KG	1KG	99%	1ton	Career Henan Chemical Co

Chlophedianol Hydrochloride
511-13-7
US $1980.00-1520.00 / mg
TargetMol Chemicals Inc.

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
511-13-7
US $0.10 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
511-13-7
US $1.00 / KG
99%
Career Henan Chemical Co

511-13-7(2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE)Related Search:

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Benzhydrol (2S)-1-[[(2R,3S)-5-CHLORO-3-(2-CHLOROPHENYL)-1-[(3,4-DIMETHOXYPHENYL)SULFONYL]-2,3-DIHYDRO-3-HYDROXY-1H-INDOL-2-YL]CARBONYL]-2-PYRROLIDINECARBOXAMIDE 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE

1of2

1-o-chlorophenyl-1-phenyl-3-dimethylamino-1-propanolhydrochloride Hydrochloric acid chlophedianol 2-Chloro-α-[2-(diMethylaMino)ethyl]-α-phenylbenzeneMethanol 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE CHLOPHEDIANOL HYDROCHLORIDE CHLOPHEDIANOL CLOFEDANOL HCL hydrochloride bayer b-186 2-chloro-alpha-(2-(dimethylamino)-ethyl)benzhydrol hydrochloride alpha-(2-dimethylaminoethyl)-o-chlorobenzhydrol 2-chloro-alpha-(2-(dimethylamino)ethyl)-benzhydro hydrochloride 1-o-chlorophenyl-1-phenyl-3-dimethylamino-1-propanol hydrochloride 2-chloro-alpha-(2-(dimethylamino)ethyl)-alpha-phenyl-benzenemethano hydro chlophedianol hydrochloride α-(2-Dimethylaminoethyl)-o-chlorobenzhydrol hydrochloride Benzhydrol, 2-chloro-α-[2-(dimethylamino)ethyl]-, hydrochloride (7CI, 8CI) Benzenemethanol, 2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl-, hydrochloride 2-Chloro-α-[2-dimethylaminoethyl] benzhydrol hydrochloride detigon coldrin clophedianolhydrochloride clofedanolhydrochloride chlorphedianol,hydrochloride bayerb-186 bayer-186 alpha-(2-dimethylaminoethyl)-o-chlorobenzhydrolhydrochloride ulone ulo sl501 sk74 refugal pectolitan detigon-bayer 2-chloro-alpha-[2-(dimethylamino)ethyl]-alpha-phenyl-benzenemethanohydro 2-chloro-alpha-(2-(dimethylamino)ethyl)-benzhydrohydrochloride 2-chloro-alpha-(2-(dimethylamino)ethyl)-alpha-phenyl-benzenemethanohydro 2-Chloro-[2-(dimethylamino)ethyl]-Phenyl-benzenemethanolhydrochloride Benzenemethanol,2-chloro-a-[2-(dimethylamino)ethyl]-a-phenyl-,hydrochloride (1:1) 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE USP/EP/BP Clofedannol HCI Chlophedianol Hcl 511-13-7 C17H20ClNOHCl Amines Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals