ChemicalBook >> CAS DataBase List >>5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
![5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Structure](CAS/GIF/131084-35-0.gif)
- CAS No.
- 131084-35-0
- Chemical Name:
- 5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
- Synonyms
- CS-1071;CP 94253;CP94253HCl;CP 94253 Free base;CP 94253 HYDROCHLORIDE;CP-94,253 dihydrochloride;3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine;4-{5-propoxy-1H-pyrrolo[3,2-b]pyridin-3-yl}-1,2,3,6-tetrahydropyridine
- CBNumber:
- CB7761214
- Molecular Formula:
- C15H19N3O
- Molecular Weight:
- 257.33
- MDL Number:
- MFCD03453293
- MOL File:
- 131084-35-0.mol
- MSDS File:
- SDS
Last updated:2023-05-04 17:34:32
| Melting point | >230°C (dec.) |
|---|---|
| Boiling point | 442.9±45.0 °C(Predicted) |
| Density | 1.166 |
| storage temp. | Desiccate at RT |
| solubility | H2O: soluble15mg/mL, clear |
| form | powder |
| pka | 14.37±0.40(Predicted) |
| color | white to beige |
| FDA UNII | FYC6YY5RYL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0588 | CP-94,253 dihydrochloride ≥98% (HPLC) | 131084-35-0 | 5mg | $119 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0588 | CP-94,253 dihydrochloride ≥98% (HPLC) | 131084-35-0 | 25mg | $481 | 2024-03-01 | Buy |
| Tocris | 1317 | CP94253hydrochloride ≥98%(HPLC) | 131084-35-0 | 10 | $210 | 2021-12-16 | Buy |
| Tocris | 1317 | CP94253hydrochloride ≥98%(HPLC) | 131084-35-0 | 50 | $822 | 2021-12-16 | Buy |
| Usbiological | 255041 | CP 94253 hydrochloride | 131084-35-0 | 10mg | $466 | 2021-12-16 | Buy |
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
CP 94253 Hydrochloride is a potent and selective serotonin 5-HT1B receptor agonist with anticonvulsant activity.
Definition
ChEBI: 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine is a pyrrolopyridine.
Biological Activity
Potent, selective 5-HT 1B agonist (K i values are 89, 2, 860, 49 and 1,600 nM for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 1D and 5-HT 2 receptors respectively). Centrally active upon systemic administration in vivo .
Biochem/physiol Actions
CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Suppliers
Global( 31)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1202 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4566 | 55 | |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4891 | 55 |
131084-35-0(5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE)Related Search:
5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
CP 94253 HYDROCHLORIDE
CP94253HCl
5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridin hydrochloride
CP 94253
3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride
CP-94,253 dihydrochloride
5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine
5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine
CS-1071
3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine
1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-
5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
CP 94253 Free base
4-{5-propoxy-1H-pyrrolo[3,2-b]pyridin-3-yl}-1,2,3,6-tetrahydropyridine
131084-35-0
C15H20N3OCl
C15H19N3OHCl
Serotonin receptor