ANTI-HUMAN WT1
- CAS No.
- Chemical Name:
- ANTI-HUMAN WT1
- Synonyms
- Anti-AN2;Anti-GUD;Anti-WAGR;Anti-WT33;ANTI-WT-1;Anti-WIT-2;Anti-D11S812E;ANTI-WT-1 MAB;ANTI-HUMAN WT1;ANTI-WT-1, HUMAN
- CBNumber:
- CB7782949
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01324002
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P305+P351+P338 |
ANTI-HUMAN WT1 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2102716 | Anti-WT1 antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2501111 | Anti-WILMS Tumor 1/WT1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | $545 | 2023-01-07 | Buy | |
| Sigma-Aldrich | SAB2500755 | Anti-PAX6 (Internal) antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | $505 | 2022-05-15 | Buy |
ANTI-HUMAN WT1 Chemical Properties,Uses,Production
Uses
Anti-WT1 antibody produced in rabbit has been used in western blotting.
General Description
Wilms tumor 1 (WT1) is a transcription factor with C-terminal zinc-finger motifs and an N-terminal proline/glutamine-rich DNA-binding domain. WT1 gene is mapped to human chromosome 11p13. WT1 expression occurs in the spleen, kidneys, gonads, and abdominal cavity lining during vertebrate development. WT1 exists as multiple transcript variants, resulting from alternative splicing at two coding exons. Evidence suggests the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.
Biochem/physiol Actions
Wilms tumor 1 (WT1) participates in the homeostasis of the adrenal glands and gonads. WT1 functions as an oncogene and its expression are observed in a majority of tumors associated with neuronal, hematopoietic, epithelial, and mesenchymal tissues. It serves as a target for cancer immune therapy. WT1 displays a tumor suppressor role in acute myeloid leukemia (AML). Mutations in the WT1 gene is also implicated in the pathophysiology of Denys-Drash syndrome (DDS) and Frasier syndrome (FS).
ANTI-HUMAN WT1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN WT1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| Vector Laboratories, Inc. | -- | vector@vectorlabs.com | United States | 631 | 80 |
| Agilent Technologies (Shanghai) Co., Ltd. | -- | United States | 736 | 80 | |
| Vision BioSystems | -- | sales.usa@vision-bio.com | United States | 542 | 74 |
| BD Biosciences | -- | United States | 5013 | 82 | |
| Zymed Laboratories Inc. | -- | United States | 3068 | 86 | |
| VWR International | -- | solutions@vwr.com | United Kingdom | 6554 | 82 |
| EMD Biosciences, Inc. | -- | technical@calbiochem.com | United States | 6529 | 66 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| Vector Laboratories, Inc. | 80 |
| Agilent Technologies (Shanghai) Co., Ltd. | 80 |
| Vision BioSystems | 74 |
| BD Biosciences | 82 |
| Zymed Laboratories Inc. | 86 |
| VWR International | 82 |
| EMD Biosciences, Inc. | 66 |