Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-

CAS No.
28192-77-0
Chemical Name:
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
Synonyms
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
CBNumber:
CB78327874
Molecular Formula:
C32H48O7S
Molecular Weight:
576.79
MDL Number:
MOL File:
28192-77-0.mol
Last updated:2023-05-27 08:28:44

Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Properties

Boiling point 674.5±55.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
pka 14.51±0.70(Predicted)

Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M301940 Methyl3-p-Toluenesulfonate-cholicAcidEster 28192-77-0 0.5g $105 2021-12-16 Buy
TRC M301940 Methyl3-p-Toluenesulfonate-cholicAcidEster 28192-77-0 5g $830 2021-12-16 Buy
Product number Packaging Price Buy
M301940 0.5g $105 Buy
M301940 5g $830 Buy

Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Chemical Properties,Uses,Production

Uses

Methyl 3-p-Toluenesulfonate-cholic Acid Ester is an intermediate used in the synthesis of Aramchol (A765150), which is a fatty acid conjugate that exhibits hypocholesterolemic effects and studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.

1448-36-8
98-59-9
28192-77-0
Synthesis of Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- from CHOLIC ACID METHYL ESTER and Tosyl chloride

Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Preparation Products And Raw materials

Raw materials

Preparation Products

Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- 28192-77-0 C32H48O7S