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ChemicalBook >> CAS DataBase List >>1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy-

1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy-

1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- Structure
1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- structure
CAS No.
931078-17-0
Chemical Name:
1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy-
Synonyms
CPI905;CPI-905;CPI 905;1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy-
CBNumber:
CB78365014
Molecular Formula:
C18H20N2O5
Molecular Weight:
344.36
MDL Number:
MFCD09360203
MOL File:
931078-17-0.mol
Last updated:2023-03-31 09:12:58
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1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- Properties

Boiling point 548.8±50.0 °C(Predicted)
Density 1.237±0.06 g/cm3(Predicted)
pka 11.89±0.10(Predicted)

1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- Chemical Properties,Uses,Production

Description

CPI-905 is a potent and selective EZH2 inhibitor (IC50 = 39.5 nM). The histone lysine methyltransferase (MT) Enhancer of Zeste Homolog 2 (EZH2) is considered an oncogenic driver in a subset of germinal center B-celllike diffuse large B cell lymphoma (GCB-DLBCL) and follicular lymphoma due to the presence of recurrent, monoallelic mutations in the EZH2 catalytic domain. .

1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- Suppliers

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1,4-Benzodioxin-6-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2,3-dihydro-8-methoxy- CPI 905 CPI905 CPI-905 931078-17-0